Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2668952 | 0.76 | PDE10A (0.47) | NPC1RAB9AKDM4EPDE10AALDH1A1 | |
| SCHEMBL9832053 | 0.73 | RAB9A (1.00) | NPC1RAB9APDE10AALDH1A1HPGD | |
| SCHEMBL9933090 | 0.71 | PDE10A (0.45) | NPC1RAB9AKDM4EPDE10AALDH1A1 | |
| SCHEMBL858832 | 0.71 | MAP4K4 (0.46) | NPC1RAB9AKDM4EPDE10AALDH1A1 | |
| SCHEMBL10921639 | 0.71 | PDE10A (0.45) | NPC1RAB9AKDM4EPDE10AALDH1A1 | |
| SCHEMBL259293 | 0.71 | PDE10A (0.45) | NPC1RAB9AKDM4EPDE10AALDH1A1 | |
| SCHEMBL7195074 | 0.71 | PDE10A (0.45) | NPC1RAB9AKDM4EPDE10AALDH1A1 | |
| SCHEMBL12989975 | 0.71 | PDE10A (0.45) | NPC1RAB9AKDM4EPDE10AALDH1A1 | |
| SCHEMBL21389568 | 0.71 | PDE10A (0.45) | NPC1RAB9AKDM4EPDE10AALDH1A1 | |
| SCHEMBL13934565 | 0.70 | RAB9A (0.42) | NPC1RAB9AKDM4EPDE10AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1315039-A2 | Low silver radiographic film with improved visual appearance | EASTMAN KODAK COMPANY (US) | 2003-05-28 | — | — | EP | disclosed |
| EP-0514450-A1 | PHOTOGRAPHIC RECORDING MATERIAL PROVIDED WITH AN ABSORBING LAYER FOR PHOTOGRAPHIC SPEED REDUCTION. | EASTMAN KODAK CO (US) | 1992-11-25 | — | — | EP | disclosed |