SCHEMBL7067176

SCHEMBL7067176

CCOC(=O)C(I)CCI

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CPB2 Q96IY4 2/20 0.38
ALOX15 P16050 1/20 0.37
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
SOAT1 P35610 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.35
TRPA1 O75762 1/20 0.34
CYP1A2 P05177 1/20 0.34
KMT2A Q03164 3/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
POLB P06746 1/20 0.33
MEN1 O00255 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7971402 0.89 CPB2 (0.41) ALDH1A1LMNAHSD17B10CPB2ALOX15
SCHEMBL2868252 0.88 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10CPB2ALOX15
SCHEMBL7973143 0.85 CPB2 (0.42) ALDH1A1LMNAHSD17B10CPB2ALOX15
SCHEMBL8932070 0.84 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10CPB2ALOX15
SCHEMBL2865545 0.84 CPB2 (0.47) ALDH1A1LMNAHSD17B10CPB2ALOX15
SCHEMBL6761975 0.84 CPB2 (0.43) ALDH1A1LMNAHSD17B10CPB2ALOX15
SCHEMBL25341569 0.84 CPB2 (0.45) ALDH1A1LMNAHSD17B10CPB2ALOX15
SCHEMBL14547304 0.81
SCHEMBL6817900 0.80 CA2 (0.44) ALDH1A1LMNAHSD17B10CPB2ALOX15
SCHEMBL7067966 0.79 ALDH1A1 (0.47) ALDH1A1L3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0827954-B1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL CO (JP) 2003-06-04 EP disclosed
US-6114543-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-09-05 US disclosed
US-5880291-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-03-09 US disclosed
EP-0827954-A1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-03-11 EP disclosed