SCHEMBL7067266

SCHEMBL7067266

CS(=O)(=O)OCCC(OS(C)(=O)=O)C(=O)Oc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TDP1 Q9NUW8 1/20 0.37
ELANE P08246 1/20 0.36
MAPT P10636 4/20 0.35
ALDH1A1 P00352 2/20 0.35
PPARG P37231 1/20 0.35
PPARA Q07869 1/20 0.35
CYP1A2 P05177 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
TMPRSS15 P98073 1/20 0.33
MEN1 O00255 1/20 0.33
THRB P10828 1/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP24A1 Q07973 1/20 0.32
NR4A2 P43354 1/20 0.32
FAAH O00519 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7959907 0.92 TDP1 (0.41) ATML3MBTL1TDP1ELANEMAPT
SCHEMBL7976065 0.91 ALDH1A1 (0.39) ATML3MBTL1TDP1ELANEMAPT
SCHEMBL7064408 0.82 ALDH1A1 (0.44) L3MBTL1TDP1ELANEALDH1A1SMN1; SMN2
SCHEMBL7064266 0.81 CA1 (0.41) L3MBTL1TDP1ALDH1A1PPARGSMN1; SMN2
SCHEMBL7064394 0.80 HCAR2 (0.40) ALDH1A1KMT2ACYP3A4
SCHEMBL7065836 0.80 MAPT (0.41) ATML3MBTL1TDP1ELANEMAPT
SCHEMBL7060903 0.77 HTT (0.39) ALDH1A1CYP1A2SMN1; SMN2KMT2A
SCHEMBL7064391 0.76 MAOB (0.36) L3MBTL1TDP1MAPTALDH1A1PPARG
SCHEMBL7066030 0.76 ALDH1A1 (0.39) ALDH1A1
SCHEMBL7973318 0.75 ALDH1A1 (0.42) L3MBTL1TDP1ELANEALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0827954-B1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL CO (JP) 2003-06-04 EP disclosed
US-6114543-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-09-05 US disclosed
US-5880291-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-03-09 US disclosed
EP-0827954-A1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-03-11 EP disclosed