Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 6/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CTRC | Q99895 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959907 | 0.96 | TDP1 (0.41) | ALDH1A1KDM4EUSP2LMNAMMP9 | |
| SCHEMBL7067266 | 0.91 | ATM (0.39) | ALDH1A1TDP1L3MBTL1ATMELANE | |
| SCHEMBL7972991 | 0.84 | ALDH1A1 (0.41) | ALDH1A1KDM4EUSP2LMNAMMP9 | |
| SCHEMBL7970070 | 0.82 | PTGES (0.40) | ALDH1A1KDM4EUSP2LMNAMMP9 | |
| SCHEMBL7959874 | 0.81 | MAPT (0.39) | TDP1L3MBTL1ATMMAPTCTRC | |
| SCHEMBL7973318 | 0.80 | ALDH1A1 (0.42) | ALDH1A1LMNATSHRTDP1L3MBTL1 | |
| SCHEMBL7976100 | 0.79 | CYP24A1 (0.37) | ALDH1A1LMNATDP1 | |
| SCHEMBL7972855 | 0.79 | PTGES (0.40) | ALDH1A1LMNATSHRTDP1L3MBTL1 | |
| SCHEMBL7973197 | 0.78 | KDM4E (0.48) | ALDH1A1KDM4EUSP2LMNAMMP9 | |
| SCHEMBL7973159 | 0.77 | MAPT (0.39) | TDP1L3MBTL1ATMELANEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172234-B1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0976729-A1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |