SCHEMBL7065836

SCHEMBL7065836

O=C(Oc1ccccc1)C(CCOS(=O)(=O)c1ccccc1)OS(=O)(=O)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.41
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PTGES O14684 1/20 0.35
PPARG P37231 1/20 0.34
PPARA Q07869 1/20 0.34
TDP1 Q9NUW8 3/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ELANE P08246 1/20 0.33
ENPP3 O14638 1/20 0.32
CA2 P00918 1/20 0.32
ENPP1 P22413 1/20 0.32
ENPP2 Q13822 1/20 0.32
CA9 Q16790 1/20 0.32
PARL Q9H300 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7973159 0.92 MAPT (0.39) MAPTATML3MBTL1PTGESTDP1
SCHEMBL7060903 0.91 HTT (0.39) PTGESSMN1; SMN2
SCHEMBL7959874 0.91 MAPT (0.39) MAPTATML3MBTL1PTGESTDP1
SCHEMBL7067274 0.85 KMT2A (0.41) ATMSMN1; SMN2CA2CA9
SCHEMBL7976225 0.84 TDP1 (0.39) PTGESTDP1SMN1; SMN2
SCHEMBL7064430 0.84 TDP1 (0.42) MAPTATMTDP1SMN1; SMN2CA2
SCHEMBL7976100 0.83 CYP24A1 (0.37) PTGESTDP1SMN1; SMN2
SCHEMBL7068104 0.83 ALDH1A1 (0.40) MAPTL3MBTL1TDP1SMN1; SMN2ELANE
SCHEMBL7066495 0.83 RAB9A (0.39) CA2CA9
SCHEMBL7067287 0.82 CA1 (0.40) L3MBTL1TDP1SMN1; SMN2CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0827954-B1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL CO (JP) 2003-06-04 EP disclosed
US-6114543-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-09-05 US disclosed
US-5880291-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-03-09 US disclosed
EP-0827954-A1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-03-11 EP disclosed