Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.37 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.37 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Serine SCHEMBL18428172 | 0.93 | ELANE (0.31) | — | |
| D-Glutamate SCHEMBL27779763 | 0.85 | GRM8 (0.40) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Arginine SCHEMBL8587129 | 0.83 | ALOX15 (0.31) | — | |
| SCHEMBL3236621 | 0.82 | NOS2 (0.36) | CYP1A2 | |
| Glutamic Acid SCHEMBL2592950 | 0.81 | GRM8 (0.38) | GRM8GRM6GRIN2DGRIN3BGSR | |
| SCHEMBL30716624 | 0.81 | QARS1 (0.40) | GRM8GRM6GRIN2DGRIN3BGSR | |
| D-Glutamate SCHEMBL27546761 | 0.81 | GRM8 (0.36) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Serine SCHEMBL17199761 | 0.81 | ALOX15 (0.41) | QARS1 | |
| Glutamic Acid SCHEMBL7654784 | 0.80 | GRM8 (0.44) | GRM8GRM6GRIN2DGRIN3BGSR | |
| D-Glutamate SCHEMBL27639981 | 0.80 | GRM8 (0.44) | GRM8GRM6GRIN2DGRIN3BGSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113373229-B | Gastric cancer related biomarker and application thereof | 福建医科大学附属第一医院 | 2022-06-24 | — | — | CN | disclosed |
| CN-114072497-A | Compositions for modulating and self-inactivating enzyme expression and methods for modulating off-target activity of enzymes | 宾夕法尼亚州大学信托人 | 2022-02-18 | — | — | CN | disclosed |
| CN-113373229-A | Gastric cancer related biomarker and application thereof | 福建医科大学附属第一医院 | 2021-09-10 | — | — | CN | disclosed |
| US-6642370-B1 | Genetic marker for autoimmune disorder | TEXAS SCOTTISH RITE HOSPITAL FOR CHILDREN | 2003-11-04 | — | — | US | disclosed |
| US-20030104404-A1 | Genetic markers for autoimmune disorder | TEXAS SCOTTISH RITE HOSPITAL FOR CHILDREN | 2003-06-05 | — | — | US | disclosed |