Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5634261 | 0.82 | ALDH1A1 (0.38) | ALDH1A1MAPTTDP1HPGDNPSR1 | |
| SCHEMBL2728279 | 0.74 | HPGD (0.49) | ALDH1A1MAPTTDP1HPGDNPSR1 | |
| SCHEMBL5633146 | 0.72 | ALDH1A1 (0.34) | ALDH1A1MAPTTDP1SMN1; SMN2L3MBTL1 | |
| SCHEMBL5633394 | 0.72 | ALDH1A1 (0.31) | ALDH1A1MAPTTDP1SMN1; SMN2L3MBTL1 | |
| SCHEMBL5634017 | 0.71 | AGTR1 (0.36) | ALDH1A1MAPTTDP1HPGDNPSR1 | |
| SCHEMBL5632839 | 0.71 | ALDH1A1 (0.36) | ALDH1A1MAPTTDP1HPGDNPSR1 | |
| SCHEMBL1101454 | 0.71 | ALDH1A1 (0.47) | ALDH1A1MAPTTDP1HPGDNPSR1 | |
| SCHEMBL11499891 | 0.69 | MGLL (0.48) | ALDH1A1MAPTTDP1HPGDNPSR1 | |
| SCHEMBL5634864 | 0.69 | TDP1 (0.50) | ALDH1A1MAPTTDP1HPGDNPSR1 | |
| SCHEMBL5632868 | 0.69 | CRHBP (0.34) | ALDH1A1SMN1; SMN2L3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4608810-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE TO TREAT HYPOPARATHYROIDISM AND OSTEOPOROSIS | Septerna, Inc. (US) | 2025-09-03 | — | — | EP | disclosed |
| WO-2024091498-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE TO TREAT HYPOPARATHYROIDISM AND OSTEOPOROSIS | SEPTERNA, INC. (US) | 2024-05-02 | — | — | WO | disclosed |
| WO-2003037262-A2 | NOVEL ANIT-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2003-05-08 | — | — | WO | disclosed |