Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 6/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 5/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.32 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7515485 | 1.00 | GPR119 (0.36) | GPR119KLK7RORCKLK5STS | |
| SCHEMBL7518553 | 0.73 | GPR119 (0.34) | GPR119KLK7RORCKLK5STS | |
| SCHEMBL7067178 | 0.73 | GPR119 (0.34) | GPR119KLK7RORCKLK5STS | |
| SCHEMBL6481828 | 0.71 | KLK7 (0.37) | GPR119KLK7RORCKLK5STS | |
| SCHEMBL7067547 | 0.69 | KDM1A (0.34) | GPR119RORCKMT2AMT-CO2ALOX5 | |
| SCHEMBL7515491 | 0.69 | KLK7 (0.36) | GPR119KLK7RORCKLK5STS | |
| SCHEMBL7067383 | 0.69 | KLK7 (0.36) | GPR119KLK7RORCKLK5STS | |
| SCHEMBL4555170 | 0.67 | GPR119 (0.37) | GPR119KLK7RORCKLK5STS | |
| SCHEMBL13108777 | 0.65 | NOTUM (0.48) | GPR119BCHE | |
| SCHEMBL18597763 | 0.65 | USP30 (0.40) | GPR119KLK7RORCKLK5STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1314041-A2 | SCREEN FOR GLUTAMATE REUPTAKE INHIBITORS, STIMULATORS, AND MODULATORS | Annovis, Inc. (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018941-A2 | SCREEN FOR GLUTAMATE REUPTAKE INHIBITORS, STIMULATORS, AND MODULATORS | ANNOVIS, INC. (US) | 2002-03-07 | — | — | WO | disclosed |