Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.30 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.30 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067952 | 0.73 | USP30 (0.33) | KDM1AGPR119RORC | |
| SCHEMBL7515485 | 0.69 | GPR119 (0.36) | MT-CO2ALOX5GPR119RORCKMT2A | |
| SCHEMBL7067385 | 0.69 | GPR119 (0.36) | MT-CO2ALOX5GPR119RORCKMT2A | |
| SCHEMBL7518553 | 0.63 | GPR119 (0.34) | KDM1AGPR119RORC | |
| SCHEMBL10920030 | 0.60 | KCNN4 (0.43) | KMT2AMAPK1 | |
| SCHEMBL6117763 | 0.59 | MAPT (0.49) | KMT2AL3MBTL1SMN1; SMN2MAPK1 | |
| SCHEMBL29769613 | 0.59 | MAPT (0.49) | KMT2AL3MBTL1SMN1; SMN2MAPK1 | |
| SCHEMBL17605695 | 0.59 | GLS (0.41) | KMT2AL3MBTL1MAPK1 | |
| SCHEMBL10344448 | 0.59 | MAPK1 (0.39) | KMT2APLA2G10PLA2G5MAPK1 | |
| SCHEMBL15977398 | 0.58 | MAPK1 (0.55) | KDM1AMAOBRORCSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1314041-A2 | SCREEN FOR GLUTAMATE REUPTAKE INHIBITORS, STIMULATORS, AND MODULATORS | Annovis, Inc. (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018941-A2 | SCREEN FOR GLUTAMATE REUPTAKE INHIBITORS, STIMULATORS, AND MODULATORS | ANNOVIS, INC. (US) | 2002-03-07 | — | — | WO | disclosed |
| EP-0809624-A1 | ALKYLCARBOXY AMINO ACIDS-MODULATORS OF THE KAINATE RECEPTOR | Bearsden Bio, Inc. (US) | 1997-12-03 | — | — | EP | disclosed |
| WO-1996025387-A1 | ALKYLCARBOXY AMINO ACIDS-MODULATORS OF THE KAINATE RECEPTOR | SYMPHONY PHARMACEUTICALS, INC. (US) | 1996-08-22 | — | — | WO | disclosed |