Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A3 | P38919 | 15/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540536 | 0.95 | EIF4A3 (0.53) | EIF4A3MEN1KMT2AMGLL | |
| SCHEMBL8540533 | 0.95 | EIF4A3 (0.53) | EIF4A3MEN1KMT2AMGLL | |
| SCHEMBL7133590 | 0.88 | RIPK1 (0.54) | MEN1KMT2AALDH1A1 | |
| SCHEMBL4657697 | 0.75 | RIPK1 (0.47) | MEN1KMT2AALDH1A1 | |
| SCHEMBL4657693 | 0.75 | RIPK1 (0.47) | MEN1KMT2AALDH1A1 | |
| SCHEMBL3888129 | 0.74 | SLC6A7 (0.57) | MEN1KMT2AMGLLALDH1A1 | |
| SCHEMBL19214123 | 0.72 | RIPK1 (0.56) | MEN1KMT2AALDH1A1 | |
| SCHEMBL19214124 | 0.72 | RIPK1 (0.56) | MEN1KMT2AALDH1A1 | |
| SCHEMBL18711396 | 0.72 | POLB (0.61) | MEN1KMT2A | |
| SCHEMBL19214118 | 0.72 | PLA2G1B (0.49) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003045381-A1 | AMINOALKYLIMIDAZOLE DERIVATIVES AND THEIR USE IN MEDICINE | MOLECULAR SKINCARE LIMITED (GB) | 2003-06-05 | — | — | WO | disclosed |