Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A3 | P38919 | 12/20 | 0.53 |
| ▸ | MGLL | Q99685 | 3/20 | 0.51 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540536 | 1.00 | EIF4A3 (0.53) | EIF4A3MGLLSLC6A7MEN1KMT2A | |
| SCHEMBL7067642 | 0.95 | EIF4A3 (0.53) | EIF4A3MGLLMEN1KMT2A | |
| SCHEMBL7133590 | 0.84 | RIPK1 (0.54) | MEN1KMT2A | |
| SCHEMBL4657697 | 0.71 | RIPK1 (0.47) | MEN1KMT2A | |
| SCHEMBL4657693 | 0.71 | RIPK1 (0.47) | MEN1KMT2A | |
| SCHEMBL15949390 | 0.71 | HPGD (0.48) | EIF4A3MGLLSLC6A7MEN1KMT2A | |
| SCHEMBL911549 | 0.71 | HPGD (0.48) | EIF4A3MGLLSLC6A7MEN1KMT2A | |
| SCHEMBL3888129 | 0.71 | SLC6A7 (0.57) | MGLLSLC6A7MEN1KMT2A | |
| SCHEMBL15949277 | 0.70 | MGLL (0.60) | MGLLSLC6A7MEN1KMT2A | |
| SCHEMBL14540882 | 0.69 | CA1 (0.81) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0683156-B1 | Acylated aminoalkanimidazoles and -triazoles | CIBA GEIGY AG (CH) | 1998-04-01 | — | — | EP | disclosed |
| US-5622982-A | ENZYME INHIBITORS; ANTIINFLAMMATORY AGENTS | SANDOZ LTD. (CH) | 1997-04-22 | — | — | US | disclosed |
| EP-0683156-A1 | Acylated aminoalkanimidazoles and -triazoles | SANDOZ LTD. (CH) | 1995-11-22 | — | — | EP | disclosed |