Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSG | P08311 | 1/20 | 0.56 |
| ▸ | CMA1 | P23946 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067645 | 1.00 | CTSG (0.56) | CTSGCMA1L3MBTL1LMNATSHR | |
| SCHEMBL7982632 | 0.81 | MMP1 (0.49) | CTSGCMA1L3MBTL1GAAHPGD | |
| SCHEMBL27522992 | 0.81 | MMP1 (0.49) | CTSGCMA1L3MBTL1GAAHPGD | |
| SCHEMBL7128547 | 0.81 | MME (0.51) | MME | |
| SCHEMBL14765234 | 0.81 | CHRNB2 (0.64) | GRIA1 | |
| SCHEMBL7128546 | 0.81 | MME (0.51) | MME | |
| SCHEMBL14761409 | 0.81 | CHRNB2 (0.64) | GRIA1 | |
| SCHEMBL14761840 | 0.80 | CHRNB2 (0.63) | GRIA1 | |
| SCHEMBL14761090 | 0.80 | CHRNB2 (0.63) | GRIA1 | |
| SCHEMBL14761872 | 0.80 | CHRNB2 (0.63) | GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060161-B1 | MATRIX METALLOPROTEINASE INHIBITORS | LEO PHARMA AS WITH SECONDARY N (DK) | 2003-06-11 | — | — | EP | disclosed |