Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.49 |
| ▸ | FCER2 | P06734 | 1/20 | 0.49 |
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27522992 | 1.00 | MMP1 (0.49) | MMP1FCER2CTSGCMA1MMP3 | |
| SCHEMBL27550386 | 0.93 | MMP1 (0.46) | MMP1CTSGCMA1MMP3MMP2 | |
| SCHEMBL7982890 | 0.88 | ACE (0.52) | MMP1FCER2MMP3MMP2MMP7 | |
| SCHEMBL7982892 | 0.88 | ACE (0.52) | MMP1FCER2MMP3MMP2MMP7 | |
| SCHEMBL7068112 | 0.86 | EPHX2 (0.47) | MMP1CTSGCMA1MMP3MMP2 | |
| SCHEMBL7068109 | 0.86 | EPHX2 (0.47) | MMP1CTSGCMA1MMP3MMP2 | |
| SCHEMBL27549172 | 0.84 | MMP2 (0.58) | MMP1MMP3MMP2 | |
| SCHEMBL7067649 | 0.81 | CTSG (0.56) | CTSGCMA1L3MBTL1GAAHPGD | |
| SCHEMBL7067645 | 0.81 | CTSG (0.56) | CTSGCMA1L3MBTL1GAAHPGD | |
| SCHEMBL7982631 | 0.81 | EPHX2 (0.48) | CTSGCMA1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277876-B1 | Matrix metalloproteinase inhibitors | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 2001-08-21 | — | — | US | disclosed |