Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 5/20 | 0.42 |
| ▸ | CES2 | O00748 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2914675 | 0.96 | NFE2L2 (0.46) | MEN1KMT2ANFE2L2CES1CES2 | |
| SCHEMBL28827764 | 0.96 | NFE2L2 (0.46) | MEN1KMT2ANFE2L2CES1CES2 | |
| Fluoride SCHEMBL11179978 | 0.93 | NFE2L2 (0.45) | MEN1KMT2ANFE2L2CES1CES2 | |
| SCHEMBL7074206 | 0.83 | SMN1; SMN2 (0.50) | MEN1KMT2AALDH1A1MAPK1POLB | |
| SCHEMBL7071425 | 0.81 | ALDH1A1 (0.52) | MEN1KMT2ACES1CES2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10530955 | 0.79 | ALDH1A1 (0.50) | MEN1KMT2ACES1CES2ALDH1A1 | |
| SCHEMBL7072098 | 0.79 | PARP10 (0.55) | ALDH1A1POLB | |
| SCHEMBL6832826 | 0.78 | NFE2L2 (0.43) | MEN1KMT2ANFE2L2CES1CES2 | |
| SCHEMBL7071041 | 0.78 | CES2 (0.50) | MEN1KMT2ACES1CES2ALDH1A1 | |
| SCHEMBL8387743 | 0.78 | MAPT (0.50) | MEN1KMT2ACES2ALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946492-B1 | NOVEL 2-FLUOROACRYLIC ACID DERIVATIVES, NOVEL MIXTURES OF HERBICIDES AND ANTIDOTES AND THE USE THEREOF | BAYER CROPSCIENCE GMBH (DE) | 2003-06-18 | — | — | EP | claimed |