SCHEMBL7071041

SCHEMBL7071041

O=C(O)C=C(F)c1ccc(F)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
BCL2L1 Q07817 1/20 0.48
BAD Q92934 1/20 0.48
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
MAPT P10636 1/20 0.46
ALDH1A1 P00352 1/20 0.43
HTT P42858 1/20 0.43
TNFRSF1A P19438 1/20 0.42
MEN1 O00255 1/20 0.42
POLB P06746 1/20 0.42
KMT2A Q03164 1/20 0.42
PTPN1 P18031 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
LTA4H P09960 1/20 0.41
MITF O75030 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8387743 0.83 MAPT (0.50) CES2CA1CA2MAPTALDH1A1
SCHEMBL2914675 0.82 NFE2L2 (0.46) CES2CES1CA1CA2MAPT
SCHEMBL28827764 0.82 NFE2L2 (0.46) CES2CES1CA1CA2MAPT
SCHEMBL7071606 0.81 CYP1A2 (0.50) CES2CES1CA1CA2MAPT
SCHEMBL7070720 0.81 ALOX15 (0.52) CES2CES1CA1CA2MAPT
SCHEMBL7071425 0.81 ALDH1A1 (0.52) CES2CES1CA2MAPTALDH1A1
SCHEMBL3165945 0.80 CES2 (0.52) CES2CES1BCL2L1BADCA1
Fluoride SCHEMBL11179978 0.80 NFE2L2 (0.45) CES2CES1CA1CA2MAPT
Hydrochloric Acid SCHEMBL10530955 0.79 ALDH1A1 (0.50) CES2CES1CA2MAPTALDH1A1
SCHEMBL7074206 0.79 SMN1; SMN2 (0.50) MAPTALDH1A1MEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0946492-B1 NOVEL 2-FLUOROACRYLIC ACID DERIVATIVES, NOVEL MIXTURES OF HERBICIDES AND ANTIDOTES AND THE USE THEREOF BAYER CROPSCIENCE GMBH (DE) 2003-06-18 EP claimed
US-5972839-A MIXTURE WITH PLANT SAFENING AGENT HOECHST SCHERING AGREVO GMBH (DE) 1999-10-26 US claimed
CN-114957170-B Ether compound ortho carbon-hydrogen bond direct monofluoroalkenyl reaction 滁州学院 2024-05-24 CN disclosed
CN-114957170-A Direct monofluoroolefination reaction of ether compound ortho-position carbon-hydrogen bond 滁州学院 2022-08-30 CN disclosed
US-5972839-A MIXTURE WITH PLANT SAFENING AGENT HOECHST SCHERING AGREVO GMBH (DE) 1999-10-26 US disclosed