SCHEMBL27784285

SCHEMBL27784285

O=C(c1ccccc1)c1c(-c2ccccc2)oc2ccccc2c1=O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.63
MEN1 O00255 4/20 0.63
ALDH1A1 P00352 4/20 0.63
MAPT P10636 4/20 0.63
LMNA P02545 3/20 0.63
HTT P42858 3/20 0.63
GAA P10253 2/20 0.63
NPSR1 Q6W5P4 1/20 0.63
KDM4E B2RXH2 4/20 0.62
CYP3A4 P08684 2/20 0.62
ALOX15 P16050 2/20 0.62
MAPK1 P28482 2/20 0.62
TP53 P04637 2/20 0.62
CA12 O43570 1/20 0.62
CA1 P00915 1/20 0.62
CA2 P00918 1/20 0.62
ABCB1 P08183 1/20 0.62
CALM1 P0DP23 1/20 0.62
AR P10275 1/20 0.62
PKM P14618 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7068281 0.89 L3MBTL1 (0.67) KMT2AMEN1ALDH1A1MAPTLMNA
SCHEMBL6527669 0.87 ALDH1A1 (0.69) KMT2AMEN1ALDH1A1MAPTLMNA
SCHEMBL311250 0.84 KDM4E (0.62) KMT2AMEN1ALDH1A1MAPTLMNA
SCHEMBL26031862 0.84 KMT2A (0.62) KMT2AMEN1ALDH1A1MAPTLMNA
SCHEMBL9873754 0.84 KDM4E (0.62) KMT2AMEN1ALDH1A1MAPTLMNA
SCHEMBL7915193 0.83 ADORA3 (0.67) KMT2AMEN1ALDH1A1MAPTLMNA
SCHEMBL1666903 0.82 CYP2C9 (0.49) KMT2AMEN1ALDH1A1MAPTLMNA
SCHEMBL1923200 0.82 KDM4E (0.59) KMT2AMEN1ALDH1A1MAPTLMNA
SCHEMBL27913159 0.82 KMT2A (0.59) KMT2AMEN1ALDH1A1MAPTLMNA
SCHEMBL9659870 0.81 KMT2A (0.62) KMT2AMEN1ALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101768146-A Method for preparing benzoyl-flavone SUOPING XU 2010-07-07 CN claimed
CN-101088046-B Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL CO 2011-05-25 CN disclosed
CN-101768146-A Method for preparing benzoyl-flavone SUOPING XU 2010-07-07 CN disclosed
CN-101768146-A Method for preparing benzoyl-flavone SUOPING XU 2010-07-07 CN disclosed
CN-101768146-A Method for preparing benzoyl-flavone SUOPING XU 2010-07-07 CN disclosed
CN-101088046-A Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL CO (JP) 2007-12-12 CN disclosed