SCHEMBL706916

SCHEMBL706916

O=C(Cl)c1cc(Br)ccc1Br

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.48
CES2 O00748 1/20 0.48
GALR3 O60755 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C9 P11712 1/20 0.48
HPGD P15428 1/20 0.48
CASP1 P29466 1/20 0.48
CYP2C19 P33261 1/20 0.48
PTPN2 P17706 2/20 0.46
PTPN1 P18031 2/20 0.46
PTPN6 P29350 1/20 0.46
KDM4E B2RXH2 1/20 0.45
GLA P06280 1/20 0.45
ALDH1A1 P00352 1/20 0.44
POLB P06746 3/20 0.44
MAPT P10636 2/20 0.44
RAB9A P51151 1/20 0.44
HSP90AA1 P07900 1/20 0.43
TLR9 Q9NR96 1/20 0.43
PLAU P00749 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31173096 0.84 HPGD (0.50) ALOX15CES2GALR3CYP1A2CYP2C9
SCHEMBL6862035 0.82 FLT1 (0.46) ALOX15CES2GALR3CYP1A2CYP2C9
SCHEMBL1669829 0.80 ALDH1A1 (0.47) HPGDCASP1KDM4EGLAALDH1A1
SCHEMBL3127332 0.80 ALOX15 (0.69) ALOX15CES2GALR3CYP1A2CYP2C9
SCHEMBL18163 0.80 ALDH1A1 (0.61) ALOX15CES2GALR3CYP1A2CYP2C9
SCHEMBL2266803 0.80 MAPT (0.38) ALOX15CES2ALDH1A1MAPT
SCHEMBL30356385 0.80 ALDH1A1 (0.61) ALOX15CES2GALR3CYP1A2CYP2C9
SCHEMBL570906 0.79 KDM4E (0.63) ALOX15CES2GALR3CYP1A2CYP2C9
SCHEMBL4649267 0.78 CES2 (0.47) ALOX15CES2ALDH1A1MAPTRAB9A
SCHEMBL16730401 0.78 ALDH1A1 (0.33) ALOX15PTPN2PTPN1PTPN6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109134875-B Preparation of chiral covalent organic framework material with L-menthol as chiral source 齐齐哈尔大学 2021-08-31 CN claimed
WO-2024181097-A1 PHOTOCURABLE COMPOSITION, METHOD FOR PRODUCING CURED ARTICLE, FILM, OPTICAL ELEMENT, IMAGE SENSOR, SOLID-STATE IMAGING ELEMENT, IMAGE DISPLAY DEVICE, AND RADICAL POLYMERIZATION INITIATOR 富士フイルム株式会社 2024-09-06 WO disclosed
CN-109134875-B Preparation of chiral covalent organic framework material with L-menthol as chiral source 齐齐哈尔大学 2021-08-31 CN disclosed
US-8124443-B2 Organic diodes and materials MARROCCO MATTHEW L (US) 2012-02-28 US disclosed
US-20100112751-A1 ORGANIC DIODES AND MATERIALS MARROCCO III MATTHEW L 2010-05-06 US disclosed
US-7655961-B2 Organic diodes and materials MAXDEM INCORPORATED (US) 2010-02-02 US disclosed
US-7442760-B2 Electroactive polymers 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-10-28 US disclosed
US-20080026135-A1 ELECTRON TRANSPORT AGENTS FOR ORGANIC ELECTRONIC DEVICES 3M INNOVATIVE PROPERTIES COMPANY 2008-01-31 US disclosed
CN-100357388-C Organic electroluminescent compositions 3M INNOVATIVE PROPERTIES CO (US) 2007-12-26 CN disclosed
US-7288329-B2 Electroluminescent devices including conjugated polymers containing an azole structure EASTMAN KODAK COMPANY (US) 2007-10-30 US disclosed
WO-2004096948-A1 ELECTRON TRANSPORT AGENTS FOR ORGANIC ELECTRONIC DEVICES 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-11-11 WO disclosed
WO-2004096783-A1 ETHYNYL CONTAINING ELECTRON TRANSPORT AGENTS AND THEIR USE IN ORGANIC LUMINESCENT DEVICES 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-11-11 WO disclosed
US-20040214037-A1 Ethynyl containing electron transport dyes and compositions 3M INNOVATIVE PROPERTIES COMPANY 2004-10-28 US disclosed
US-20040214036-A1 Electron transport agents for organic electronic devices 3M INNOVATIVE PROPERTIES COMPANY 2004-10-28 US disclosed
US-20040062930-A1 Electroactive polymers 3M INNOVATIVE PROPERTIES COMPANY 2004-04-01 US disclosed
US-20040062947-A1 Organic electroluminescent compositions 3M INNOVATIVE PROPERTIES COMPANY 2004-04-01 US disclosed
US-3959217-A N-(halobenzoyl)-4,5-dibromo-3,6-methanohexahydrophthalimides VELSICOL CHEMICAL CORPORATION (US) 1976-05-25 US disclosed
US-3959216-A N-(Halobenzoyl) hexahalo-3,5-methanotetrahydrophthalimides VELSICOL CHEMICAL CORPORATION (US) 1976-05-25 US disclosed
US-3953397-A N-(halobenzoyl)-3,4-dibromohexahydrophthalimides VELSICOL CHEMICAL CORPORATION (US) 1976-04-27 US disclosed
US-3950307-A FIREPROOFING POLYMERS VELSICOL CHEMICAL CORPORATION (US) 1976-04-13 US disclosed