SCHEMBL6862035

SCHEMBL6862035

O=C(Cl)c1ccc(Br)cc1Br

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT1 P17948 1/20 0.46
FLT4 P35916 1/20 0.46
KDR P35968 1/20 0.46
KMT2A Q03164 3/20 0.46
HPGD P15428 2/20 0.46
ALOX15 P16050 2/20 0.44
DGAT1 O75907 1/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
CES2 O00748 1/20 0.43
GALR3 O60755 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
CASP1 P29466 1/20 0.43
CYP2C19 P33261 1/20 0.43
HSP90AA1 P07900 1/20 0.43
TLR9 Q9NR96 1/20 0.43
KDM4E B2RXH2 1/20 0.41
GLA P06280 1/20 0.41
ALDH1A1 P00352 4/20 0.40
MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31173096 0.84 HPGD (0.50) KMT2AHPGDALOX15DGAT1CES2
SCHEMBL706916 0.82 ALOX15 (0.48) HPGDALOX15DGAT1CES2GALR3
SCHEMBL27892673 0.81 HPGD (0.58) FLT1FLT4KDRKMT2AHPGD
SCHEMBL257466 0.80 FLT1 (0.49) FLT1FLT4KDRKMT2AHPGD
SCHEMBL30526110 0.80 FLT1 (0.49) FLT1FLT4KDRKMT2AHPGD
SCHEMBL2268166 0.80 ALDH1A1 (0.37) FLT1FLT4KDRHPGDALOX15
SCHEMBL27838132 0.80 CES2 (0.45) KMT2AALOX15CES2KDM4EALDH1A1
SCHEMBL1164132 0.80 FLT1 (0.51) FLT1FLT4KDRHPGDCASP1
SCHEMBL2780747 0.79 KDM4E (0.57) KMT2AHPGDALOX15DGAT1L3MBTL1
SCHEMBL31402606 0.79 KMT2A (0.51) FLT1FLT4KDRKMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040062947-A1 Organic electroluminescent compositions 3M INNOVATIVE PROPERTIES COMPANY 2004-04-01 US disclosed
CN-1031378-C Combating insect infestation in rice ROHM & HAAS (US) 1996-03-27 CN disclosed
CN-1046835-A Go out and remove the method for rice insect pest ROHM & HAAS (US) 1990-11-14 CN disclosed
EP-0031436-B1 A METHOD FOR THE CLEAVAGE OF SILOXANES HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) 1984-02-15 EP disclosed
US-4310680-A METAL OR METAL COMPOUND CATALYST DYNAMIT NOBEL AG (DE) 1982-01-12 US disclosed
EP-0031436-A2 A method for the cleavage of siloxanes HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) 1981-07-08 EP disclosed
US-4160862-A ANTIINFLAMMATORY STERLING DRUG INC. (US) 1979-07-10 US disclosed
US-4021431-A ANTIINFLAMMATORY AGENTS STERLING DRUG INC. (US) 1977-05-03 US disclosed
US-3959216-A N-(Halobenzoyl) hexahalo-3,5-methanotetrahydrophthalimides VELSICOL CHEMICAL CORPORATION (US) 1976-05-25 US disclosed
US-3959217-A N-(halobenzoyl)-4,5-dibromo-3,6-methanohexahydrophthalimides VELSICOL CHEMICAL CORPORATION (US) 1976-05-25 US disclosed
US-3953397-A N-(halobenzoyl)-3,4-dibromohexahydrophthalimides VELSICOL CHEMICAL CORPORATION (US) 1976-04-27 US disclosed
US-3950307-A FIREPROOFING POLYMERS VELSICOL CHEMICAL CORPORATION (US) 1976-04-13 US disclosed
US-3939162-A Anthrapyrimidine dyes BASF AKTIENGESELLSCHAFT (DT) 1976-02-17 US disclosed