Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12903863 | 0.81 | DHFR (0.46) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL14182479 | 0.79 | HSD17B10 (0.41) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL4448803 | 0.77 | DHFR (0.40) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL30944688 | 0.76 | DNMT1 (0.47) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL30122801 | 0.76 | DNMT1 (0.47) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL367587 | 0.76 | DNMT1 (0.47) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL10434031 | 0.75 | ALDH1A1 (0.44) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL27263879 | 0.75 | ALDH1A1 (0.53) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL29787010 | 0.74 | DNMT1 (0.59) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL196007 | 0.74 | DNMT1 (0.59) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944638-B1 | CIS-BRIDGED METAL COMPLEXES | BASF AG (DE) | 2003-06-11 | — | — | EP | disclosed |
| EP-0944638-A1 | CIS-BRIDGED METAL COMPLEXES | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998025939-A1 | CIS-BRIDGED METAL COMPLEXES | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-18 | — | — | WO | disclosed |