Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.48 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.48 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.48 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7069339 | 0.82 | CNR1 (0.55) | CNR1F2PRSS1TPSAB1TPSD1 | |
| SCHEMBL7074851 | 0.79 | GAA (0.63) | CNR1F2PRSS1TPSAB1TPSD1 | |
| SCHEMBL7074867 | 0.79 | TGM2 (0.55) | CNR1F2PRSS1TPSAB1TPSD1 | |
| SCHEMBL7071366 | 0.79 | F2 (0.51) | CNR1F2PRSS1TPSAB1TPSD1 | |
| SCHEMBL7074313 | 0.78 | CYP2C9 (0.60) | F2PRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL7074218 | 0.78 | ALDH1A1 (0.67) | CNR1F2PRSS1TPSAB1TPSD1 | |
| SCHEMBL7651893 | 0.77 | KMT2A (0.53) | CNR1F2PRSS1TPSAB1TPSD1 | |
| SCHEMBL7070571 | 0.77 | GAA (0.58) | CNR1F2PRSS1TPSAB1TPSD1 | |
| SCHEMBL7074100 | 0.77 | MAPT (0.53) | CNR1TDP1TRPV4ALDH1A1MAPT | |
| SCHEMBL7074161 | 0.77 | KMT2A (0.58) | CNR1TDP1F10ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |