SCHEMBL706959

SCHEMBL706959

CC[Si](F)(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.38
ESR1 P03372 2/20 0.34
ESR2 Q92731 1/20 0.34
NR1H2 P55055 3/20 0.32
NR1H3 Q13133 3/20 0.32
PSIP1 O75475 1/20 0.32
ALDH1A1 P00352 2/20 0.32
TSHR P16473 2/20 0.32
MAPT P10636 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
LMNA P02545 2/20 0.31
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30
SLC9A1 P19634 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL707327 0.80 TP53 (0.35) TP53ESR1ESR2NR1H2NR1H3
SCHEMBL704994 0.79 TP53 (0.38) TP53ESR1ESR2NR1H2NR1H3
SCHEMBL702836 0.79 TP53 (0.38) TP53ESR1ESR2NR1H2NR1H3
SCHEMBL706161 0.78 ESR1 (0.32) ESR1ESR2NR1H2NR1H3ALDH1A1
SCHEMBL704305 0.78 ESR1 (0.32) ESR1ESR2NR1H2NR1H3ALDH1A1
SCHEMBL16061095 0.77 NR1H2 (0.40) NR1H2NR1H3TSHRLMNA
SCHEMBL28120878 0.76 ESR1 (0.31) ESR1ESR2
SCHEMBL988676 0.75 NR1H2 (0.43) TP53ESR1ESR2NR1H2NR1H3
SCHEMBL707750 0.75 ESR1 (0.44) TP53ESR1ESR2NR1H2NR1H3
SCHEMBL707200 0.74 ALDH1A1 (0.33) ESR1ESR2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238771-A1 SUPPORTED RARE EARTH CATALYSTS AND CATALYTIC CH BORYLATION OF HYDROCARBONS IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2024-07-18 US claimed
US-20240238771-A1 SUPPORTED RARE EARTH CATALYSTS AND CATALYTIC CH BORYLATION OF HYDROCARBONS IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2024-07-18 US disclosed
US-11367902-B2 Lithium secondary battery including electrolyte containing monofluorosilane compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-06-21 US disclosed
US-10547085-B2 Lithium secondary battery including electrolyte containing monofluorosilane compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-01-28 US disclosed
US-20180219258-A1 LITHIUM SECONDARY BATTERY INCLUDING ELECTROLYTE CONTAINING MONOFLUOROSILANE COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-08-02 US disclosed
US-20180219258-A1 LITHIUM SECONDARY BATTERY INCLUDING ELECTROLYTE CONTAINING MONOFLUOROSILANE COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-08-02 US disclosed
US-8791221-B2 Addition-curable metallosiloxane compound DAICEL CORPORATION (JP) 2014-07-29 US disclosed
EP-2650319-A1 ADDITION-CURABLE METALLOSILOXANE COMPOUND Daicel Corporation (JP) 2013-10-16 EP disclosed
US-20130267653-A1 ADDITION-CURABLE METALLOSILOXANE COMPOUND DAICEL CORPORATION (JP) 2013-10-10 US disclosed
US-8124239-B2 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2012-02-28 US disclosed
US-20100155121-A1 SILICA FILM FORMING MATERIAL, SILICA FILM AND METHOD OF MANUFACTURING THE SAME, MULTILAYER WIRING STRUCTURE AND METHOD OF MANUFACTURING THE SAME, AND SEMICONDUCTOR DEVICE AND METHOD OF MANUFACTURING THE SAME FUJITSU LIMITED (JP) 2010-06-24 US disclosed
US-7659357-B2 Precursor organosilicon polymer of 1,2-Bis(dimethylethoxysilyl)ethane, 1,4-bis(dimethylethoxysilyl)benzene, tetraethoxysilane, methyltriethoxysilane, phenyltriethoxysilane; dielectric (DE) films having etching/chemical/moisture resistance; adhesion; low DE constant; minimal wiring delay; high speed FUJITSU LIMITED (JP) 2010-02-09 US disclosed
US-20070026689-A1 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2007-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238771-A1 SUPPORTED RARE EARTH CATALYSTS AND CATALYTIC CH BORYLATION OF HYDROCARBONS HAO2, SCO2, SOD1 TP53 4264/4885ESR1 465/4885ESR2 359/4885
US-20130267653-A1 ADDITION-CURABLE METALLOSILOXANE COMPOUND B2M, MSI2, MNS1 TP53 3501/4885ESR1 2638/4885ESR2 2436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.