Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PKLR | P30613 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27550445 | 0.96 | GAA (0.57) | GAALMNACNR1L3MBTL1POLB | |
| SCHEMBL1945062 | 0.82 | L3MBTL1 (0.80) | GAALMNACNR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL1429534 | 0.81 | L3MBTL1 (0.66) | GAALMNACNR1L3MBTL1POLB | |
| SCHEMBL7074277 | 0.81 | F10 (0.67) | GAALMNAL3MBTL1SMN1; SMN2F10 | |
| SCHEMBL9613675 | 0.80 | F10 (0.63) | GAALMNAL3MBTL1POLBUSP2 | |
| SCHEMBL7071911 | 0.80 | L3MBTL1 (0.61) | GAALMNACNR1L3MBTL1POLB | |
| SCHEMBL7074108 | 0.80 | F10 (0.54) | GAALMNAL3MBTL1POLBUSP2 | |
| SCHEMBL7074160 | 0.80 | F10 (0.54) | GAALMNAL3MBTL1POLBUSP2 | |
| SCHEMBL751856 | 0.79 | ALDH1A1 (0.61) | GAALMNACNR1L3MBTL1POLB | |
| SCHEMBL7075851 | 0.79 | USP2 (0.61) | GAALMNAL3MBTL1POLBUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |