Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.51 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CETP | P11597 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.44 |
| ▸ | HTR3B | O95264 | 3/20 | 0.44 |
| ▸ | HTR3A | P46098 | 3/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4419949 | 0.99 | MAOA (0.51) | MAOAMAOBADRB1DGAT1THRB | |
| SCHEMBL3074024 | 0.89 | DGAT1 (0.58) | MAOAMAOBDGAT1THRBCA12 | |
| SCHEMBL8221014 | 0.83 | L3MBTL1 (0.59) | ADRB1THRBL3MBTL1HTR3EHTR3B | |
| SCHEMBL20076229 | 0.83 | NR1I2 (0.44) | MAOAMAOBDGAT1THRBCA12 | |
| SCHEMBL7070577 | 0.79 | SMN1; SMN2 (0.52) | MAOAMAOBSIGMAR1MAPT | |
| SCHEMBL21956060 | 0.79 | CETP (0.60) | ADRB1CETPACVR1HTR3EHTR3B | |
| SCHEMBL8226429 | 0.79 | L3MBTL1 (0.46) | MAOAMAOBL3MBTL1TP53MAPT | |
| SCHEMBL8226248 | 0.79 | L3MBTL1 (0.46) | MAOAMAOBTHRBL3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL21876097 | 0.77 | CETP (0.59) | ADRB1CETPACVR1HTR3EHTR3B | |
| SCHEMBL13415301 | 0.77 | L3MBTL1 (0.69) | MAOAMAOBCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |
| CN-1272107-A | Benzamidine derivatives as factor Xa inhibitors | MERCK PATENT GMBH (DE) | 2000-11-01 | — | — | CN | disclosed |