Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 15/20 | 0.80 |
| ▸ | MMP2 | P08253 | 14/20 | 0.80 |
| ▸ | MMP1 | P03956 | 12/20 | 0.80 |
| ▸ | MMP7 | P09237 | 5/20 | 0.80 |
| ▸ | MMP9 | P14780 | 5/20 | 0.80 |
| ▸ | Q9HBH1 | 1/20 | 0.61 | |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.55 |
| ▸ | MMP14 | P50281 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7070053 | 1.00 | MMP3 (0.80) | MMP3MMP2MMP1MMP7MMP9 | |
| SCHEMBL8398532 | 0.89 | MMP3 (1.00) | MMP3MMP2MMP1MMP7MMP9 | |
| SCHEMBL14545737 | 0.89 | MMP3 (1.00) | MMP3MMP2MMP1MMP7MMP9 | |
| SCHEMBL8400266 | 0.84 | MMP3 (0.77) | MMP3MMP2MMP1MMP7MMP9 | |
| SCHEMBL8397206 | 0.82 | MMP3 (0.79) | MMP3MMP2MMP1MMP7MMP9 | |
| SCHEMBL8396712 | 0.82 | MMP3 (0.79) | MMP3MMP2MMP1MMP7MMP9 | |
| SCHEMBL8397183 | 0.81 | PDF (0.90) | MMP3MMP2MMP1MMP7MMP9 | |
| SCHEMBL7383365 | 0.81 | BIRC2 (0.69) | MMP3MMP2MMP1MMP7MMP9 | |
| SCHEMBL7969452 | 0.81 | BIRC2 (0.69) | MMP3MMP2MMP1MMP7MMP9 | |
| SCHEMBL4818599 | 0.79 | MMP3 (0.82) | MMP3MMP2MMP1MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060161-B1 | MATRIX METALLOPROTEINASE INHIBITORS | LEO PHARMA AS WITH SECONDARY N (DK) | 2003-06-11 | — | — | EP | claimed |
| US-6277876-B1 | Matrix metalloproteinase inhibitors | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 2001-08-21 | — | — | US | claimed |
| EP-1060161-B1 | MATRIX METALLOPROTEINASE INHIBITORS | LEO PHARMA AS WITH SECONDARY N (DK) | 2003-06-11 | — | — | EP | disclosed |
| US-6277876-B1 | Matrix metalloproteinase inhibitors | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 2001-08-21 | — | — | US | disclosed |