SCHEMBL8397183

SCHEMBL8397183

CCCCCCCCCCCCCCCCC(CC(=O)NO)C(=O)N[C@H](C(=O)N(C)C)C(C)(C)C

nearest known ligand 0.90

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PDF Q9HBH1 4/20 0.90
MMP3 P08254 12/20 0.73
MMP2 P08253 12/20 0.73
MMP1 P03956 9/20 0.73
MMP7 P09237 5/20 0.73
MMP9 P14780 1/20 0.73
BIRC2 Q13490 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4812129 0.95 PDF (1.00) PDFMMP3MMP2MMP1MMP7
SCHEMBL8055256 0.87 PDF (0.90) PDFMMP3MMP2MMP1MMP7
SCHEMBL8400277 0.87 PDF (0.90) PDFMMP3MMP2MMP1MMP7
SCHEMBL8400266 0.87 MMP3 (0.77) PDFMMP3MMP2MMP1MMP7
SCHEMBL8398532 0.85 MMP3 (1.00) PDFMMP3MMP2MMP1MMP7
SCHEMBL14545737 0.85 MMP3 (1.00) PDFMMP3MMP2MMP1MMP7
SCHEMBL8396712 0.84 MMP3 (0.79) PDFMMP3MMP2MMP1MMP7
SCHEMBL8397206 0.84 MMP3 (0.79) PDFMMP3MMP2MMP1MMP7
SCHEMBL7070053 0.81 MMP3 (0.80) PDFMMP3MMP2MMP1MMP7
SCHEMBL7070048 0.81 MMP3 (0.80) PDFMMP3MMP2MMP1MMP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0763012-B1 SUCCINYL HYDROXAMIC ACID, N-FORMYL-N-HYDROXY AMINO CARBOXYLIC ACID AND SUCCINIC ACID AMIDE DERIVATIVES AS METALLOPROTEASE INHIBITORS BRITISH BIOTECH PHARM (GB) 1999-06-09 EP claimed
EP-0763012-B1 SUCCINYL HYDROXAMIC ACID, N-FORMYL-N-HYDROXY AMINO CARBOXYLIC ACID AND SUCCINIC ACID AMIDE DERIVATIVES AS METALLOPROTEASE INHIBITORS BRITISH BIOTECH PHARM (GB) 1999-06-09 EP disclosed