Sugi Predict

Sugi Predict / Compounds / Hydroxyamine

Hydroxyamine

Hydroxyamine

SCHEMBL7070102

CCCCCCC(Sc1cccc(OC)c1)C(=O)O.NO

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ PPARG P37231 12/20 0.64
▸ ALOX5 P09917 10/20 0.64
▸ PPARA Q07869 10/20 0.64
▸ PTGES O14684 8/20 0.52
▸ MTNR1A P48039 6/20 0.48
▸ MTNR1B P49286 6/20 0.48
▸ FOLH1 Q04609 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7070103 0.88 ALOX5 (0.53) PPARGALOX5PPARAPTGESMTNR1A
Hydroxyamine SCHEMBL7465088 0.85 PPARG (0.63) PPARGALOX5PPARAPTGES
SCHEMBL6931961 0.85 MMP9 (0.56) PPARGALOX5PPARAMTNR1AMTNR1B
SCHEMBL6935114 0.82 PPARG (0.65) PPARGALOX5PPARAPTGES
SCHEMBL6930527 0.81 PPARG (0.67) PPARGALOX5PPARAPTGES
SCHEMBL9099036 0.80 PPARG (0.64) PPARGALOX5PPARAPTGESFOLH1
SCHEMBL8356987 0.80 PPARG (0.64) PPARGALOX5PPARAPTGESFOLH1
SCHEMBL22612343 0.80 PPARG (0.64) PPARGALOX5PPARAPTGESFOLH1
SCHEMBL9099026 0.80 PPARG (0.64) PPARGALOX5PPARAPTGESFOLH1
SCHEMBL5081085 0.79 PPARG (0.66) PPARGALOX5PPARAPTGESFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0970046-B1 N-HYDROXY-2-(ALKYL, ARYL, OR HETEROARYL SULFANYL, SULFINYL OR SULFONYL)-3-SUBSTITUTED ALKYL, ARYL OR HETEROARYLAMIDES AS MATRIX METALLOPROTEINASE INHIBITORS WYETH CORP (US) 2003-12-10 — — EP disclosed