Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.53 |
| ▸ | PPARG | P37231 | 4/20 | 0.53 |
| ▸ | PPARA | Q07869 | 3/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 10/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.42 |
| ▸ | TUBB | P07437 | 2/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyamine SCHEMBL7070102 | 0.88 | PPARG (0.64) | ALOX5PPARGPPARAMTNR1AMTNR1B | |
| SCHEMBL7465093 | 0.85 | PPARG (0.51) | ALOX5PPARGPPARAPTGES | |
| SCHEMBL6931961 | 0.85 | MMP9 (0.56) | ALOX5PPARGPPARAMTNR1AMTNR1B | |
| SCHEMBL7650530 | 0.77 | MMP9 (0.46) | ALOX5PPARGPPARATSHRMAPK1 | |
| SCHEMBL8856146 | 0.76 | PPARG (0.52) | ALOX5PPARGPPARAALDH1A1PTGES | |
| SCHEMBL6927165 | 0.75 | ALOX5 (0.53) | ALOX5PPARGPPARAPTGES | |
| SCHEMBL6929348 | 0.75 | ALOX5 (0.53) | ALOX5PPARGPPARAPTGES | |
| SCHEMBL6934185 | 0.74 | ALOX5 (0.53) | ALOX5PPARGPPARAPTGES | |
| Hydroxyamine SCHEMBL7465088 | 0.73 | PPARG (0.63) | ALOX5PPARGPPARAPTGES | |
| SCHEMBL29756836 | 0.72 | MTNR1A (0.52) | ALOX5PPARGPPARAMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970046-B1 | N-HYDROXY-2-(ALKYL, ARYL, OR HETEROARYL SULFANYL, SULFINYL OR SULFONYL)-3-SUBSTITUTED ALKYL, ARYL OR HETEROARYLAMIDES AS MATRIX METALLOPROTEINASE INHIBITORS | WYETH CORP (US) | 2003-12-10 | — | — | EP | disclosed |