SCHEMBL7070145

SCHEMBL7070145

C=CN(C=O)CCC(=O)OCC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.40
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.37
NR1I2 O75469 1/20 0.37
PGR P06401 1/20 0.37
ADORA3 P0DMS8 1/20 0.37
PTGS2 P35354 1/20 0.37
PDE4D Q08499 1/20 0.37
ALDH1A1 P00352 4/20 0.36
TRPA1 O75762 1/20 0.36
TSHR P16473 3/20 0.36
LMNA P02545 1/20 0.36
POLB P06746 1/20 0.36
CYP3A4 P08684 1/20 0.35
ALOX15 P16050 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8559074 0.85 DGKA (0.34) ALDH1A1TSHRHSD17B10TDP1MEN1
SCHEMBL5972268 0.84 CYP1A2 (0.41) CYP1A2MGAMGAASIMGAM2
SCHEMBL8749111 0.83 TSHR (0.46) ALDH1A1TSHRL3MBTL1
SCHEMBL8559071 0.82 THRB (0.39) SMN1; SMN2ALDH1A1TSHRCYP3A4
SCHEMBL8665088 0.82 TSHR (0.46) GAASMN1; SMN2ALDH1A1TSHRCYP3A4
SCHEMBL8560839 0.82 TSHR (0.38) ALDH1A1TSHRCYP3A4L3MBTL1
SCHEMBL8560501 0.81 KMT2A (0.48) MGAMGAASIMGAM2ALDH1A1
SCHEMBL8590382 0.81 TSHR (0.41) TSHR
SCHEMBL8558720 0.81 TSHR (0.41) ALDH1A1TSHRCYP3A4L3MBTL1
SCHEMBL15613108 0.78 CYP1A2 (0.37) CYP1A2MGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0879916-B1 Process for the treatment of fibrous materials made from natural or synthetic polyamide CIBA SC HOLDING AG (CH) 2003-06-25 EP disclosed
US-6039768-A TREATMENT WITH SPECIFIC HOMO- OR COPOLYMERS CONTAINING VINYL AMINE MONOMERS; IMPROVED FASTNESS TO WET TREATMENTS CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-03-21 US disclosed
US-5948125-A Method of treating dyed, natural or synthetic polyamide fibre materials CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-09-07 US disclosed
EP-0879916-A2 Process for the treatment of dyed fibrous materials made from natural or synthetic polyamide Ciba SC Holding AG (CH) 1998-11-25 EP disclosed
US-5728878-A USEFUL AS MONOMERS AIR PRODUCTS AND CHEMICALS, INC. (US) 1998-03-17 US disclosed
EP-0816351-A1 Functional N-vinylformamides, process for their preparation and their use in free radical polymerisation reactions AIR PRODUCTS AND CHEMICALS, INC. (US) 1998-01-07 EP disclosed
EP-0812949-A2 Process for the treatment of dyed fibrous cellulosic materials Ciba SC Holding AG (CH) 1997-12-17 EP disclosed
US-5679738-A Aqueous polymeric emulsions incorporating polymerized units of michael adducts of N-vinylformamide AIR PRODUCTS AND CHEMICALS, INC. (US) 1997-10-21 US disclosed
US-5672731-A USEFUL AS MONOMERS IN FREE RADICAL POLYMERIZATION, PARTICULARLY AS COMPONENTS OF PHOTOCURABLE COATINGS AIR PRODUCTS AND CHEMICALS, INC. (US) 1997-09-30 US disclosed
EP-0683183-B1 Michael adducts of n-vinylformamide and acrylic and methacrylic esters AIR PROD & CHEM (US) 1997-09-03 EP disclosed
EP-0763522-A1 N-vinylformamide/alkyl acrylate michael adducts AIR PRODUCTS AND CHEMICALS, INC. (US) 1997-03-19 EP disclosed
EP-0683183-A1 Michael adducts of n-vinylformamide and acrylic and methacrylic esters AIR PRODUCTS AND CHEMICALS, INC. (US) 1995-11-22 EP disclosed
US-5463110-A A 3-(N-vinylformamido)propionate in photocurable coatings; reactive diluents; solvents; hydrophobic; glass transition temperatures; kinetics AIR PRODUCTS AND CHEMICALS, INC. (US) 1995-10-31 US disclosed