SCHEMBL7070321

SCHEMBL7070321

Cc1cccc2c1Sc1ccccc1N2c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 1/20 0.41
MAOA P21397 1/20 0.40
BCHE P06276 10/20 0.40
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
NOX1 Q9Y5S8 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
ALDH1A1 P00352 1/20 0.34
ACHE P22303 1/20 0.33
MGLL Q99685 1/20 0.33
MAPK1 P28482 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
ALOX12 P18054 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HTR1A P08908 1/20 0.33
ADRB3 P13945 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16773180 0.91 HDAC6 (0.40) HDAC6MAOABCHEMEN1KMT2A
SCHEMBL24858858 0.90 MGLL (0.37) BCHEMEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL21692930 0.88 BCHE (0.43) HDAC6MAOABCHEMEN1KMT2A
SCHEMBL22045006 0.86 MEN1 (0.37) HDAC6BCHEMEN1KMT2ANOX1
SCHEMBL22250981 0.80 HDAC6 (0.41) HDAC6MAOABCHEMEN1KMT2A
SCHEMBL342426 0.80 HDAC6 (0.56) HDAC6MAOABCHEMEN1KMT2A
SCHEMBL29387100 0.80 HDAC6 (0.56) HDAC6MAOABCHEMEN1KMT2A
SCHEMBL20935948 0.80 HDAC6 (0.38) HDAC6MAOABCHEMEN1KMT2A
SCHEMBL16940888 0.80 BCHE (0.41) HDAC6MAOABCHEMEN1KMT2A
SCHEMBL16945823 0.80 HDAC6 (0.41) HDAC6MAOABCHEMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US claimed
CN-113026036-B Method for synthesizing sulfur ylide compounds by using continuous flow electrochemical oxidation 南京工业大学 2022-06-07 CN disclosed
CN-113026036-A Method for synthesizing sulfur ylide compounds by using continuous flow electrochemical oxidation 南京工业大学 2021-06-25 CN disclosed
US-20170077410-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND USE THEREOF LUMINESCENCE TECHNOLOGY CORP. (TW) 2017-03-16 US disclosed
US-20160372679-A1 COMPOUNDS FOR ORGANIC ELECTROLUMINESCENCE DEVICE LUMINESCENCE TECHNOLOGY CORP. (TW) 2016-12-22 US disclosed
US-20160211456-A1 PHENANTHRO[9,10-b]TETRAPHENYLENE DERIVATIVE AND USE THEREOF LUMINESCENCE TECHNOLOGY CORP. 2016-07-21 US disclosed
US-9190619-B2 Compound for organic electroluminescence device LUMINESCENCE TECHNOLOGY CORP (TW) 2015-11-17 US disclosed
US-20150214492-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE LUMINESCENCE TECHNOLOGY CORP (TW) 2015-07-30 US disclosed
EP-0458502-B1 Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom DOW GLOBAL TECHNOLOGIES INC (US) 2003-06-18 EP disclosed
CN-1050618-C Latent Catalysts, Cure-inhibited epxoy resin compositions and laminates prepared therefrom DOW CHEMICAL CO (US) 2000-03-22 CN disclosed
US-5503937-A MIXTURE OF A COMPOUND HAVING MORE THAN ONE EPOXY GROUP, A DIHYDRIC PHENOLIC COMPOUND AND A LATENT CATALYST COMPRISING A SALT OF AN N-HETEROCYCLIC COMPOUND AND AN ACID HAVING A STRONG NUCLEOPHILIC ANION; COATINGS/MOLDINGS; STORAGE THE DOW CHEMICAL COMPANY (US) 1996-04-02 US disclosed
CN-1118794-A Latent Catalysts, Cure-inhibited epxoy resin compositions and laminates prepared therefrom DOW CHEMICAL CO (US) 1996-03-20 CN disclosed
CN-1118793-A Latent catalysts, cure-inhibited epxoy resin compositions and laminates prepared therefrom DOW CHEMICAL CO (US) 1996-03-20 CN disclosed
EP-0553887-A2 Catalysts and epoxy resin composition containing the same THE DOW CHEMICAL COMPANY (US) 1993-08-04 EP disclosed
US-5169473-A Complex of an onium, arsenic or amine compound and boric acid; advanced polyepoxides; storage stability THE DOW CHEMICAL COMPANY (US) 1992-12-08 US disclosed
US-5134239-A Quaterinary indolizine compound THE DOW CHEMICAL COMPANY (US) 1992-07-28 US disclosed
CN-1056699-A Latent catalysts and cure-inhibited epoxy resin compositions and laminates made therefrom DOW CHEMICAL CO (US) 1991-12-04 CN disclosed
EP-0458502-A2 Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom THE DOW CHEMICAL COMPANY (US) 1991-11-27 EP disclosed
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US disclosed
EP-0328020-A2 Use of a catalyst in epoxy compositions THE DOW CHEMICAL COMPANY (US) 1989-08-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160372679-A1 COMPOUNDS FOR ORGANIC ELECTROLUMINESCENCE DEVICE CCNE2, CYP3A4, CCNE1 HDAC6 3437/4885MAOA 2870/4885BCHE 2223/4885
US-20150214492-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SLCO4C1, LEF1, SLCO2B1 HDAC6 4547/4885MAOA 3625/4885BCHE 3163/4885
US-20160211456-A1 PHENANTHRO[9,10-b]TETRAPHENYLENE DERIVATIVE AND USE THEREOF POP1, TERB1, AP2B1 HDAC6 4572/4885MAOA 3575/4885BCHE 4234/4885
US-20170077410-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND USE THEREOF HBS1L, EML4, EBPL HDAC6 4719/4885MAOA 1207/4885BCHE 1511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.