Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.42 |
| ▸ | MMP9 | P14780 | 6/20 | 0.42 |
| ▸ | MMP1 | P03956 | 5/20 | 0.42 |
| ▸ | MMP8 | P22894 | 4/20 | 0.42 |
| ▸ | MMP7 | P09237 | 3/20 | 0.42 |
| ▸ | FCER2 | P06734 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.40 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7072801 | 0.88 | MMP2 (0.56) | MMP2MMP9MMP1MMP8MMP7 | |
| SCHEMBL7067053 | 0.78 | CNR1 (0.42) | MMP8 | |
| SCHEMBL7069865 | 0.74 | CNR1 (0.41) | MMP8 | |
| SCHEMBL8399907 | 0.73 | MMP2 (0.55) | MMP2MMP9MMP1MMP7MMP3 | |
| SCHEMBL7983199 | 0.68 | MMP1 (0.58) | MMP2MMP9MMP1MMP8MMP7 | |
| SCHEMBL7983204 | 0.68 | MMP1 (0.58) | MMP2MMP9MMP1MMP8MMP7 | |
| SCHEMBL21758201 | 0.67 | CYP1A2 (0.55) | ANPEPRNPEPDNPEP | |
| Isobutylbenzene SCHEMBL27478984 | 0.65 | NPC1 (0.56) | MMP2MMP9MMP1MMP8MMP7 | |
| Isobutylbenzene SCHEMBL5343232 | 0.65 | EPHX1 (0.58) | ALOX5 | |
| SCHEMBL6271204 | 0.65 | MMP1 (0.46) | MMP2MMP9MMP1MMP8MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060161-B1 | MATRIX METALLOPROTEINASE INHIBITORS | LEO PHARMA AS WITH SECONDARY N (DK) | 2003-06-11 | — | — | EP | claimed |
| US-6277876-B1 | Matrix metalloproteinase inhibitors | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 2001-08-21 | — | — | US | claimed |
| EP-1060161-B1 | MATRIX METALLOPROTEINASE INHIBITORS | LEO PHARMA AS WITH SECONDARY N (DK) | 2003-06-11 | — | — | EP | disclosed |
| US-6277876-B1 | Matrix metalloproteinase inhibitors | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 2001-08-21 | — | — | US | disclosed |