Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 8/20 | 0.58 |
| ▸ | MMP2 | P08253 | 7/20 | 0.58 |
| ▸ | MMP9 | P14780 | 7/20 | 0.58 |
| ▸ | MMP8 | P22894 | 6/20 | 0.58 |
| ▸ | FCER2 | P06734 | 4/20 | 0.58 |
| ▸ | MMP7 | P09237 | 3/20 | 0.58 |
| ▸ | MMP3 | P08254 | 2/20 | 0.58 |
| ▸ | ACE | P12821 | 1/20 | 0.58 |
| ▸ | MMP12 | P39900 | 2/20 | 0.58 |
| ▸ | MMP13 | P45452 | 2/20 | 0.58 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983199 | 1.00 | MMP1 (0.58) | MMP1MMP2MMP9MMP8FCER2 | |
| SCHEMBL7135106 | 0.90 | ACE (0.49) | MMP1MMP2MMP9MMP8FCER2 | |
| SCHEMBL7982890 | 0.85 | ACE (0.52) | MMP1MMP2MMP9MMP8FCER2 | |
| SCHEMBL7982892 | 0.85 | ACE (0.52) | MMP1MMP2MMP9MMP8FCER2 | |
| SCHEMBL4635129 | 0.79 | MMP2 (0.76) | MMP1MMP2MMP9MMP8FCER2 | |
| SCHEMBL4635134 | 0.79 | MMP2 (0.76) | MMP1MMP2MMP9MMP8FCER2 | |
| SCHEMBL7128547 | 0.77 | MME (0.51) | ACEMME | |
| SCHEMBL7128546 | 0.77 | MME (0.51) | ACEMME | |
| SCHEMBL7135100 | 0.76 | MME (0.48) | MMP1MMP2MMP9MMP8FCER2 | |
| SCHEMBL7068112 | 0.76 | EPHX2 (0.47) | MMP1MMP2MMP9MMP7MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277876-B1 | Matrix metalloproteinase inhibitors | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 2001-08-21 | — | — | US | disclosed |