SCHEMBL7070565

SCHEMBL7070565

Clc1cccc2c1C(c1cccc3ccccc13)c1ccccc1C2c1cccc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.50
CYP1A2 P05177 2/20 0.50
KDM1A O60341 1/20 0.44
MEN1 O00255 5/20 0.40
KMT2A Q03164 5/20 0.40
GAA P10253 4/20 0.40
POLB P06746 1/20 0.40
TP53 P04637 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
RCE1 Q9Y256 1/20 0.37
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 1/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
KEAP1 Q14145 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ACHE P22303 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30829395 0.87 MEN1 (0.44) CYP2A6CYP1A2MEN1KMT2AGAA
SCHEMBL6675754 0.72 KDM1A (0.53) CYP2A6CYP1A2KDM1AMEN1KMT2A
SCHEMBL19854 0.69 CYP2A6 (1.00) CYP2A6CYP1A2ALDH1A1CYP3A4HPGD
SCHEMBL27987885 0.69 CYP2A6 (1.00) CYP2A6CYP1A2ALDH1A1CYP3A4HPGD
SCHEMBL31310956 0.69 CYP2A6 (1.00) CYP2A6CYP1A2ALDH1A1CYP3A4HPGD
SCHEMBL29351228 0.69 CYP2A6 (1.00) CYP2A6CYP1A2ALDH1A1CYP3A4HPGD
SCHEMBL29971658 0.69 CACNB4 (0.44) CYP2A6CYP1A2MEN1KMT2AGAA
SCHEMBL668166 0.68 CYP2C9 (0.49) KDM1AMEN1KMT2AL3MBTL1RCE1
SCHEMBL31289355 0.68 CYP2A6 (0.50) CYP2A6CYP1A2KDM1AMEN1KMT2A
Ammonia Solution, Strong SCHEMBL21063791 0.68 ALDH1A1 (0.56) CYP2A6CYP1A2KDM1AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6613458-B2 Benzo(a)perylene derivative dopant CITYU RESEARCH LTD. (HK) 2003-09-02 US disclosed
US-20030082403-A1 Organic electroluminescent elements INTELLECTUAL VENTURES II LLC 2003-05-01 US disclosed