Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10310250 | 0.83 | PKM (0.55) | PKMRAB9AALDH1A1NPC1MAPT | |
| SCHEMBL8674157 | 0.83 | TAAR1 (0.61) | PKMRAB9AALDH1A1NPC1MAPT | |
| SCHEMBL7783342 | 0.79 | EPHX1 (0.73) | RAB9AALDH1A1NPC1MAPTKDM4E | |
| SCHEMBL13195715 | 0.77 | ALDH1A1 (0.58) | PKMRAB9AALDH1A1NPC1MAPT | |
| SCHEMBL12717314 | 0.76 | SMN1; SMN2 (0.64) | PKMRAB9AALDH1A1NPC1MAPT | |
| SCHEMBL14433963 | 0.75 | ALDH1A1 (0.73) | PKMRAB9AALDH1A1NPC1MAPT | |
| SCHEMBL24197137 | 0.74 | PKM (0.50) | PKMRAB9AALDH1A1NPC1MAPT | |
| SCHEMBL24196748 | 0.73 | PKM (0.49) | PKMRAB9AALDH1A1NPC1MAPT | |
| SCHEMBL28226345 | 0.72 | HPGD (0.72) | RAB9AALDH1A1NPC1KDM4EHTT | |
| SCHEMBL14521487 | 0.72 | SMN1; SMN2 (0.68) | ALDH1A1MAPTKDM4EALOX12SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030125331-A1 | Cyclohexenyl-ethyl-thiourea compounds and use | PARKER HUGHES INSTITUTE | 2003-07-03 | — | — | US | disclosed |
| US-20030125331-A1 | Cyclohexenyl-ethyl-thiourea compounds and use | PARKER HUGHES INSTITUTE | 2003-07-03 | — | — | US | disclosed |
| US-20030125331-A1 | Cyclohexenyl-ethyl-thiourea compounds and use | PARKER HUGHES INSTITUTE | 2003-07-03 | — | — | US | disclosed |
| US-6469034-B1 | TREATMENT OF HIV INFECTION, INCLUDING MUTANT, DRUG-SENSITIVE, DRUG- RESISTANT, AND MULTI-DRUG RESISTANT STRAINS | PARKER HUGHES INSTITUTE | 2002-10-22 | — | — | US | disclosed |
| US-6469034-B1 | TREATMENT OF HIV INFECTION, INCLUDING MUTANT, DRUG-SENSITIVE, DRUG- RESISTANT, AND MULTI-DRUG RESISTANT STRAINS | PARKER HUGHES INSTITUTE | 2002-10-22 | — | — | US | disclosed |
| US-6469034-B1 | TREATMENT OF HIV INFECTION, INCLUDING MUTANT, DRUG-SENSITIVE, DRUG- RESISTANT, AND MULTI-DRUG RESISTANT STRAINS | PARKER HUGHES INSTITUTE | 2002-10-22 | — | — | US | disclosed |
| EP-1194149-A1 | CYCLOHEXENYL-ETHYL-THIOUREA COMPOUNDS AND USE | Parker Hughes Institute (US) | 2002-04-10 | — | — | EP | disclosed |
| WO-2000078315-A1 | CYCLOHEXENYL-ETHYL-THIOUREA COMPOUNDS AND USE | PARKER HUGHES INSTITUTE (US) | 2000-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125331-A1 | Cyclohexenyl-ethyl-thiourea compounds and use | TPMT, DNTT, BHMT | PKM 3893/4885RAB9A 3078/4885ALDH1A1 3359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.