Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7783342 | 0.86 | EPHX1 (0.73) | TAAR1ALDH1A1SMN1; SMN2MAPK1RAB9A | |
| SCHEMBL7070830 | 0.83 | PKM (0.63) | TAAR1ALDH1A1SMN1; SMN2ALOX15RAB9A | |
| SCHEMBL10310250 | 0.83 | PKM (0.55) | TAAR1ALDH1A1SMN1; SMN2POLBALOX15 | |
| SCHEMBL12717314 | 0.83 | SMN1; SMN2 (0.64) | TAAR1ALDH1A1SMN1; SMN2ALOX15MAPK1 | |
| SCHEMBL28226345 | 0.79 | HPGD (0.72) | TAAR1ALDH1A1POLBRAB9ANPC1 | |
| SCHEMBL14521487 | 0.79 | SMN1; SMN2 (0.68) | TAAR1ALDH1A1SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL13195715 | 0.77 | ALDH1A1 (0.58) | TAAR1ALDH1A1SMN1; SMN2ALOX15RAB9A | |
| SCHEMBL13374714 | 0.77 | HPGD (0.47) | TAAR1ALDH1A1SMN1; SMN2POLBALOX15 | |
| SCHEMBL23374499 | 0.76 | TAAR1 (0.74) | TAAR1ALDH1A1SMN1; SMN2POLBRAB9A | |
| SCHEMBL6318345 | 0.76 | ALDH1A1 (0.59) | TAAR1ALDH1A1SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776940-A | COMPOUNDS FOR TREATMENT OF SEPTIC SHOCK, ANTIINFLAMMATORY AND ANTIALLERGENS | GLAXO WELLCOME INC. (US) | 1998-07-07 | — | — | US | disclosed |