Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.69 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7129800 | 0.84 | MAPT (0.80) | L3MBTL1MAPTSRD5A2NPC1RAB9A | |
| Phenyl Propionic Acid SCHEMBL6534964 | 0.84 | KEAP1 (0.95) | FFAR1KEAP1MAPTFFAR4HDAC3 | |
| Phenyl Propionic Acid SCHEMBL10575939 | 0.83 | KEAP1 (0.83) | FFAR1KEAP1L3MBTL1MAPTFFAR4 | |
| SCHEMBL12394493 | 0.82 | FFAR1 (1.00) | FFAR1KEAP1MAPTFFAR4HDAC3 | |
| Phenyl Propionic Acid SCHEMBL29619843 | 0.82 | KEAP1 (1.00) | FFAR1KEAP1MAPTFFAR4HDAC3 | |
| Phenyl Propionic Acid SCHEMBL235064 | 0.82 | KEAP1 (1.00) | FFAR1KEAP1MAPTFFAR4HDAC3 | |
| Phenyl Propionic Acid SCHEMBL13618844 | 0.82 | KEAP1 (1.00) | FFAR1KEAP1MAPTFFAR4HDAC3 | |
| Phenyl Propionic Acid SCHEMBL3419 | 0.82 | KEAP1 (1.00) | FFAR1KEAP1MAPTFFAR4HDAC3 | |
| Phenyl Propionic Acid SCHEMBL27523271 | 0.82 | KEAP1 (1.00) | FFAR1KEAP1MAPTFFAR4HDAC3 | |
| SCHEMBL8896718 | 0.82 | NPC1 (0.59) | L3MBTL1MAPTSRD5A2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1179940-C | Novel 1,2-diphenyl-2-propen-1-one derivatives | ������ҩ��ʽ���� | 2004-12-15 | — | — | CN | disclosed |
| EP-1142865-B1 | NOVEL 1,2-DIPHENYL-2-PROPEN-1-ONE DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2003-06-18 | — | — | EP | disclosed |
| US-6395932-B1 | AMINOALKYL-1,2-DIPHENYL-2-PROPEN-1-ONE WHICH LOWER INTRAOCULAR PRESSURE BY CAUSING MORPHOLOGICAL CHANGE IN TRABECULAR MESHWORK CELLS. | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |
| EP-1142865-A1 | NOVEL 1,2-DIPHENYL-2-PROPEN-1-ONE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |