SCHEMBL7071203

SCHEMBL7071203

C=Cc1ccc(C(=O)C(C)(C)OC)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 2/20 0.41
TAS1R1 Q7RTX1 2/20 0.41
ALDH1A1 P00352 3/20 0.39
TDP1 Q9NUW8 1/20 0.36
TRPA1 O75762 1/20 0.36
CES1 P23141 1/20 0.36
THRA P10827 1/20 0.34
THRB P10828 1/20 0.34
F3 P13726 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
SRC P12931 1/20 0.33
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
RARA P10276 1/20 0.32
RARB P10826 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13838707 0.81 TAS1R3 (0.43) TAS1R3TAS1R1ALDH1A1TDP1TRPA1
SCHEMBL10001141 0.81 ALDH1A1 (0.46) TAS1R3TAS1R1ALDH1A1TDP1THRA
SCHEMBL803878 0.79 ALDH1A1 (0.44) TAS1R3TAS1R1ALDH1A1TDP1THRA
SCHEMBL10782676 0.78 ALDH1A1 (0.42) TAS1R3TAS1R1ALDH1A1TDP1THRA
SCHEMBL10712634 0.77 TDP1 (0.52) ALDH1A1TDP1CES1CA2MAPT
SCHEMBL6676984 0.76 PPARA (0.49) ALDH1A1TDP1CES1CA1CA2
SCHEMBL11299913 0.76 CES1 (0.46) CES1CA1CA2ADRB2ADRB1
SCHEMBL18678827 0.76 TPMT (0.45) CES1CA1CA2SRC
SCHEMBL20135443 0.76 CA1 (0.55) ALDH1A1TDP1CA1CA2MAPT
SCHEMBL3689915 0.76 HPGD (0.52) ALDH1A1CES1CA1CA2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250353265-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC (CH) 2025-11-20 US claimed
US-12391014-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2025-08-19 US claimed
EP-4532187-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2025-04-09 EP claimed
US-20230382065-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-30 US claimed
WO-2023228106-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-30 WO claimed
US-20250353265-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC (CH) 2025-11-20 US disclosed
US-12391014-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2025-08-19 US disclosed
EP-4532187-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2025-04-09 EP disclosed
US-20230382065-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-30 US disclosed
WO-2023228106-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-30 WO disclosed
EP-1216142-A4 THERMOFORMABLE OPHTHALMIC LENS NOVARTIS AG (CH) 2003-06-11 EP disclosed
EP-1216142-A1 THERMOFORMABLE OPHTHALMIC LENS Wesley Jessen Corporation (US) 2002-06-26 EP disclosed
WO-2001005578-A1 THERMOFORMABLE OPHTHALMIC LENS WESLEY-JESSEN CORPORATION (US) 2001-01-25 WO disclosed
EP-0161463-B1 POLYMERIC OR POLYMERISABLE AROMATIC-ALIPHATIC KETONES SUITABLE FOR USE AS POLYMERISATION PHOTOINITIATORS FRATELLI LAMBERTI S.p.A. (IT) 1989-02-01 EP disclosed
US-4672079-A KINETICS; ADDITION POLYMERIZATION FRATELLI LAMBERTI S.P.A. (IT) 1987-06-09 US disclosed
EP-0161463-A1 Polymeric or polymerisable aromatic-aliphatic ketones suitable for use as polymerisation photoinitiators FRATELLI LAMBERTI S.p.A. (IT) 1985-11-21 EP disclosed