Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10001141 | 0.86 | ALDH1A1 (0.46) | ALDH1A1TAS1R3TAS1R1TDP1THRA | |
| SCHEMBL3979952 | 0.83 | CA2 (0.38) | ALDH1A1TDP1CA2MAPTMEN1 | |
| SCHEMBL6421760 | 0.83 | TAS1R3 (0.46) | ALDH1A1TAS1R3TAS1R1TDP1THRA | |
| SCHEMBL11298330 | 0.82 | CA2 (0.46) | ALDH1A1CA2TSHRSMN1; SMN2MLYCD | |
| SCHEMBL10782676 | 0.82 | ALDH1A1 (0.42) | ALDH1A1TAS1R3TAS1R1TDP1THRA | |
| SCHEMBL3676731 | 0.82 | ALDH1A1 (0.54) | ALDH1A1CA2MLYCDALDH5A1ABAT | |
| SCHEMBL26676883 | 0.80 | THRB (0.58) | ALDH1A1TDP1THRATHRBCA2 | |
| SCHEMBL7071203 | 0.79 | TAS1R3 (0.41) | ALDH1A1TAS1R3TAS1R1TDP1THRA | |
| SCHEMBL6257475 | 0.78 | TP53 (0.39) | ALDH1A1TDP1CA2TSHRMAPT | |
| SCHEMBL23419327 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TAS1R3TAS1R1TDP1THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250353265-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2025-11-20 | — | — | US | claimed |
| US-12391014-B2 | Method for making embedded hydrogel contact lenses | ALCON INC. (CH) | 2025-08-19 | — | — | US | claimed |
| EP-4532187-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2025-04-09 | — | — | EP | claimed |
| US-20230382065-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2023-11-30 | — | — | US | claimed |
| WO-2023228106-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2023-11-30 | — | — | WO | claimed |
| EP-0161463-B1 | POLYMERIC OR POLYMERISABLE AROMATIC-ALIPHATIC KETONES SUITABLE FOR USE AS POLYMERISATION PHOTOINITIATORS | FRATELLI LAMBERTI S.p.A. (IT) | 1989-02-01 | — | — | EP | claimed |
| US-4672079-A | KINETICS; ADDITION POLYMERIZATION | FRATELLI LAMBERTI S.P.A. (IT) | 1987-06-09 | — | — | US | claimed |
| EP-0161463-A1 | Polymeric or polymerisable aromatic-aliphatic ketones suitable for use as polymerisation photoinitiators | FRATELLI LAMBERTI S.p.A. (IT) | 1985-11-21 | — | — | EP | claimed |
| US-20250353265-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2025-11-20 | — | — | US | disclosed |
| US-12410114-B2 | Process for the preparation of α-functionalized ketones | IGM GROUP B.V. (NL) | 2025-09-09 | — | — | US | disclosed |
| US-12391014-B2 | Method for making embedded hydrogel contact lenses | ALCON INC. (CH) | 2025-08-19 | — | — | US | disclosed |
| EP-4532187-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2025-04-09 | — | — | EP | disclosed |
| US-20230382065-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2023-11-30 | — | — | US | disclosed |
| WO-2023228106-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2023-11-30 | — | — | WO | disclosed |
| WO-1991003002-A1 | PHOTO-CROSSLINKED POLYMERS FOR NON-LINEAR OPTICS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-03-07 | — | — | WO | disclosed |
| EP-0161463-B1 | POLYMERIC OR POLYMERISABLE AROMATIC-ALIPHATIC KETONES SUITABLE FOR USE AS POLYMERISATION PHOTOINITIATORS | FRATELLI LAMBERTI S.p.A. (IT) | 1989-02-01 | — | — | EP | disclosed |
| US-4672079-A | KINETICS; ADDITION POLYMERIZATION | FRATELLI LAMBERTI S.P.A. (IT) | 1987-06-09 | — | — | US | disclosed |
| US-4672079-A | KINETICS; ADDITION POLYMERIZATION | FRATELLI LAMBERTI S.P.A. (IT) | 1987-06-09 | — | — | US | disclosed |
| EP-0161463-A1 | Polymeric or polymerisable aromatic-aliphatic ketones suitable for use as polymerisation photoinitiators | FRATELLI LAMBERTI S.p.A. (IT) | 1985-11-21 | — | — | EP | disclosed |
| EP-0161463-A1 | Polymeric or polymerisable aromatic-aliphatic ketones suitable for use as polymerisation photoinitiators | FRATELLI LAMBERTI S.p.A. (IT) | 1985-11-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12410114-B2 | Process for the preparation of α-functionalized ketones | PCCA, PRKCD, AKR1C1 | ALDH1A1 203/4885TAS1R3 3507/4885TAS1R1 3278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.