Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 known ✓ | P32745 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | Q9HBH1 | 1/20 | 0.38 | |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.38 |
| ▸ | NPY4R | P50391 | 2/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5846772 | 0.98 | SSTR3 (0.47) | SSTR3SMN1; SMN2ITGA4ITGB7F2 | |
| 4-Nitroaniline SCHEMBL3439260 | 0.90 | ITGA4 (0.40) | SSTR3ITGA4ITGB7F2QRFPR | |
| SCHEMBL30073980 | 0.88 | SSTR3 (0.47) | SSTR3SMN1; SMN2PDFMEN1KMT2A | |
| Acetic Acid SCHEMBL7129802 | 0.87 | ITGA4 (0.40) | ITGA4ITGB7F2QRFPRPARP14 | |
| SCHEMBL30585153 | 0.87 | QRFPR (0.49) | SSTR3QRFPRNPY1R | |
| Hydrochloric Acid SCHEMBL9763709 | 0.86 | SSTR3 (0.41) | SSTR3F2GAAPDFPARP14 | |
| Hydrochloric Acid SCHEMBL9763347 | 0.83 | PDF (0.44) | SSTR3SMN1; SMN2PDFPARP14NPY4R | |
| SCHEMBL236067 | 0.82 | SIRT5 (0.51) | — | |
| SCHEMBL14264834 | 0.82 | SIRT5 (0.51) | — | |
| SCHEMBL14286269 | 0.82 | SIRT5 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355196-B1 | Process for producing direct tooling mold and method for using the same | VANTICO INC. | 2002-03-12 | — | — | US | claimed |
| EP-0862742-B1 | ASSAY FOR BLOOD CLOTTING FACTORS VIII AND IX | OKLAHOMA MED RES FOUND (US) | 2003-06-11 | — | — | EP | disclosed |
| EP-1066144-B1 | PROCESS FOR PRODUCING DIRECT TOOLING MOLD AND METHOD FOR USING THE SAME | VANTICO AG (CH) | 2003-06-11 | — | — | EP | disclosed |
| US-6355196-B1 | Process for producing direct tooling mold and method for using the same | VANTICO INC. | 2002-03-12 | — | — | US | disclosed |
| EP-1066144-A1 | PROCESS FOR PRODUCING DIRECT TOOLING MOLD AND METHOD FOR USING THE SAME | Vantico AG (CH) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999047329-A1 | PROCESS FOR PRODUCING DIRECT TOOLING MOLD AND METHOD FOR USING THE SAME | VANTICO AG (CH) | 1999-09-23 | — | — | WO | disclosed |
| EP-0862742-A1 | ASSAY FOR BLOOD CLOTTING FACTORS VIII AND IX | Oklahoma Medical Research Foundation (US) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997019357-A1 | ASSAY FOR BLOOD CLOTTING FACTORS VIII AND IX | OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) | 1997-05-29 | — | — | WO | disclosed |