SCHEMBL7781874

SCHEMBL7781874

C=CCCCCCCCCCCCCCCCC.CCCCCCCCCCCCCCCCCC[Si](C)(C)O[SiH2]C

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.53
ALDH1A1 P00352 2/20 0.42
LMNA P02545 1/20 0.35
FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7907283 0.91 TSHR (0.37) TSHRALDH1A1LMNA
SCHEMBL7071644 0.86 TSHR (0.36) TSHRLMNA
SCHEMBL3058859 0.86 TSHR (0.36) TSHRLMNA
SCHEMBL790048 0.86 TSHR (0.36) TSHRLMNA
SCHEMBL7601810 0.84 TSHR (0.32) TSHR
SCHEMBL28250268 0.78
SCHEMBL8432714 0.77 TSHR (0.41) TSHRALDH1A1LMNA
SCHEMBL10843332 0.76 TSHR (0.70) TSHRALDH1A1FAAH
SCHEMBL4610326 0.76 TSHR (0.70) TSHRALDH1A1FAAH
SCHEMBL10842401 0.76 TSHR (0.70) TSHRALDH1A1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0750491-B1 DEODORANT AND ANTIPERSPIRANT COMPOSITIONS COLGATE PALMOLIVE CO (US) 2001-11-07 EP disclosed
EP-0750491-A1 DEODORANT AND ANTIPERSPIRANT COMPOSITIONS THE MENNEN COMPANY (US) 1997-01-02 EP disclosed
WO-1995024887-A1 DEODORANT AND ANTIPERSPIRANT COMPOSITIONS THE MENNEN COMPANY (US) 1995-09-21 WO disclosed