SCHEMBL707169

SCHEMBL707169

CC(C)O[SiH2]c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TSHR P16473 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
PDCD1 Q15116 1/20 0.32
CD274 Q9NZQ7 1/20 0.32
LMNA P02545 3/20 0.32
MAOA P21397 2/20 0.32
MAOB P27338 1/20 0.32
CA4 P22748 1/20 0.32
TAAR1 Q96RJ0 4/20 0.31
SLC6A2 P23975 2/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
CYP2A6 P11509 1/20 0.31
ADORA2A P29274 1/20 0.31
ADORA1 P30542 1/20 0.31
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL676009 0.86
SCHEMBL2959747 0.82 CA12 (0.30)
SCHEMBL5091206 0.81 PDCD1 (0.30) PDCD1CD274
SCHEMBL2961097 0.79 ALDH1A1 (0.32) ALDH1A1L3MBTL1
SCHEMBL3298602 0.78 CA4 (0.33) TDP1CA4
SCHEMBL16309500 0.78 HCAR2 (0.39) ALDH1A1LMNATAAR1ADRA2AADRA2C
SCHEMBL28618668 0.78 MEN1 (0.46) ALDH1A1L3MBTL1TDP1PDCD1CD274
SCHEMBL1172632 0.75 MAPT (0.38) ALDH1A1TSHRTDP1MAOAACHE
SCHEMBL22551519 0.75 IDO1 (0.31)
SCHEMBL28935390 0.74 MEN1 (0.39) ALDH1A1L3MBTL1TDP1LMNAHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109796293-B Method for synthesizing aromatic aldehyde by catalyzing and oxidizing allyl aromatic compound with iron 南京师范大学 2021-09-07 CN claimed
CN-106748690-B Method for synthesizing ketone by catalyzing alkylene oxide with iron 南京师范大学 2020-06-12 CN claimed
US-20200112057-A1 ALKALI ION CONDUCTING PLASTIC CRYSTALS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2020-04-09 US claimed
CN-107216242-B Method for synthesizing aromatic aldehyde, aromatic ketone and aromatic ester by oxidizing alkyl aromatic compound under catalysis of iron 南京师范大学 2020-04-03 CN claimed
US-20190020060-A1 ALKALI ION CONDUCTING PLASTIC CRYSTALS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2019-01-17 US claimed
US-20180195936-A1 Solid Phase Coatings for Microextraction MOXTEK, INC. 2018-07-12 US claimed
US-20260132143-A1 HETEROCYCLIC INHIBITORS OF KRAS G12C MUTANT PROTEINS AND USES THEREOF AMGEN INC. (US) 2026-05-14 US disclosed
US-12478621-B2 Substituted aminoquinolones as dgkalpha inhibitors for immune activation DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) 2025-11-25 US disclosed
US-12473405-B2 Polyorganosiloxane, polyorganosiloxane composition, cured product, polyorganosiloxane-containing electrolytic solution for electrolytic capacitor, and electrolytic capacitor using same MITSUBISHI CHEMICAL CORPORATION (JP) 2025-11-18 US disclosed
EP-4598917-A1 HETEROCYCLIC INHIBITORS OF KRAS G12C MUTANT PROTEINS AND USES THEREOF Amgen Inc. (US) 2025-08-13 EP disclosed
EP-4598916-A1 HETEROCYCLIC INHIBITORS OF KRAS G12C MUTANT PROTEINS AND USES THEREOF Amgen Inc. (US) 2025-08-13 EP disclosed
CN-120005195-A Composition for room temperature vulcanized transparent silicone rubber and preparation method thereof 湖北鑫金鹏新材料有限公司 2025-05-16 CN disclosed
WO-2025053278-A1 ORGANOPOLYSILOXANE, ORGANOPOLYSILOXANE COMPOSITION, CURED PRODUCT THEREOF, ORGANOPOLYSILOXANE FOR NEAR-INFRARED OPTICAL WAVEGUIDE, ORGANOPOLYSILOXANE COMPOSITION FOR NEAR-INFRARED OPTICAL WAVEGUIDE, CURED PRODUCT FOR NEAR-INFRARED OPTICAL WAVEGUIDE, NEAR-INFRARED OPTICAL WAVEGUIDE, NEAR-INFRARED OPTICAL TRANSMISSION MEMBER, AND NEAR-INFRARED OPTICAL WAVEGUIDE PRODUCTION METHOD 三菱ケミカル株式会社 2025-03-13 WO disclosed
US-20070026689-A1 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2007-02-01 US disclosed
CN-1296374-C Method for producing triorgano-monoalkoxysilanes and method for producing triorgano-monochlorosilanes HOKKO CHEM IND CO (JP) 2007-01-24 CN disclosed
CN-1837221-A Production processes for triorganomonochlorosilanes HOKKO CHEM IND CO (JP) 2006-09-27 CN disclosed
CN-1612886-A Method for producing triorgano-monoalkoxysilanes and method for producing triorgano-monochlorosilanes HOKKO CHEM IND CO (JP) 2005-05-04 CN disclosed
CN-1536023-A Porous membrane shaping composition, preparation method of porous membrane, porous membrane intercalation insulating film and semiconductor device ��Խ��ѧ��ҵ��ʽ���� 2004-10-13 CN disclosed
US-6667410-B2 Reducing an alpha-beta-unsaturated ketone to an alpha-hydroxyketone in presence of a catalyst containing manganes complex and a reducing agent BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2003-12-23 US disclosed
US-20020120170-A1 Conversion of alpha,beta-unsaturated ketones and alpha,beta-unsaturated esters into alpha-hydroxy ketones and alpha-hydroxy esters using Mn(III) catalyst, phenylsilane and dioxygen BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM 2002-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132143-A1 HETEROCYCLIC INHIBITORS OF KRAS G12C MUTANT PROTEINS AND USES THEREOF KRAS, NRAS, HRAS ALDH1A1 2638/4885L3MBTL1 1026/4885TSHR 4091/4885
US-20020120170-A1 Conversion of alpha,beta-unsaturated ketones and alpha,beta-unsaturated esters into alpha-hydroxy ketones and alpha-hydroxy esters using Mn(III) catalyst, phenylsilane and dioxygen HSD17B7, CYP17A1, HSD17B1 ALDH1A1 505/4885L3MBTL1 4093/4885TSHR 3616/4885
US-12478621-B2 Substituted aminoquinolones as dgkalpha inhibitors for immune activation DGKK, DGKG, DGKA ALDH1A1 3915/4885L3MBTL1 3833/4885TSHR 3319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.