Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.39 |
| ▸ | TPSD1 | Q9BZJ3 | 4/20 | 0.39 |
| ▸ | TPSG1 | Q9NRR2 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7072182 | 0.95 | ACSS2 (0.42) | ACSS2HPGDLMNAALDH1A1NPC1 | |
| SCHEMBL7071857 | 0.90 | ACSS2 (0.39) | ACSS2HPGDLMNAALDH1A1POLB | |
| SCHEMBL7069834 | 0.88 | PDE4A (0.43) | HPGDNPC1RAB9APOLBTPSAB1 | |
| SCHEMBL7075729 | 0.88 | HPGD (0.40) | ACSS2HPGDLMNAPOLBTPSAB1 | |
| SCHEMBL7075109 | 0.88 | ACSS2 (0.40) | ACSS2TPSAB1TPSD1TPSG1 | |
| SCHEMBL7068181 | 0.87 | TPSAB1 (0.41) | ACSS2HPGDLMNANPC1RAB9A | |
| SCHEMBL7070392 | 0.87 | TPSAB1 (0.41) | ACSS2HPGDLMNATP53ALDH1A1 | |
| SCHEMBL7068373 | 0.87 | TPSAB1 (0.39) | ACSS2HPGDLMNANPC1POLB | |
| SCHEMBL7072012 | 0.86 | TPSAB1 (0.40) | ACSS2HPGDLMNANPC1RAB9A | |
| SCHEMBL7068114 | 0.85 | TPSAB1 (0.38) | ACSS2HPGDLMNAPOLBTPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030212120-A1 | Compositions comprising a substituted benzimidazole useful for treating immunomediated inflammatory disorders | AXYS PHARMACEUTICALS, INC. (US) | 2003-11-13 | — | — | US | disclosed |
| US-6562854-B2 | Antiinflammatory agents; respiratory system disorders | AXYS PHARMACEUTICALS, INC. | 2003-05-13 | — | — | US | disclosed |
| US-20010053779-A1 | Novel compounds and compositions for treating diseases asociated with protease activity | Celera Corporation | 2001-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010053779-A1 | Novel compounds and compositions for treating diseases asociated with protease activity | CMA1, CPA3, TPSG1 | ACSS2 609/4885HPGD 1524/4885LMNA 2467/4885 |
| US-20030212120-A1 | Compositions comprising a substituted benzimidazole useful for treating immunomediated inflammatory disorders | CMA1, TPSG1, TPSD1 | ACSS2 746/4885HPGD 591/4885LMNA 3929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.