SCHEMBL7072202

SCHEMBL7072202

C[Si](C)(C)c1c(F)c(F)cc(Br)c1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30977759 1.00
SCHEMBL2858470 0.73 ALOX5AP (0.30)
SCHEMBL1043011 0.69 CA12 (0.35)
SCHEMBL2170112 0.69 KDM4E (0.33)
SCHEMBL5426089 0.69 PGR (0.31)
SCHEMBL5417623 0.69
SCHEMBL334330 0.69 KDM1A (0.31)
SCHEMBL665856 0.69 DGAT1 (0.30)
SCHEMBL22769992 0.67 CA12 (0.33)
SCHEMBL4601309 0.67 CA12 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4608820-A1 HETEROCYCLIC COMPOUNDS CAPABLE OF ACTIVATING STING Boehringer Ingelheim International GmbH (DE) 2025-09-03 EP disclosed
US-20240174641-A1 HETEROCYCLIC COMPOUNDS CAPABLE OF ACTIVATING STING BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2024-05-30 US disclosed
WO-2024089006-A1 HETEROCYCLIC COMPOUNDS CAPABLE OF ACTIVATING STING BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2024-05-02 WO disclosed
EP-1002786-B1 Process for the preparation of trifluorobenzoic acids CLARIANT GMBH (DE) 2003-06-18 EP disclosed
US-6362365-B1 DEFLUORINATION OF THE TETRAFUOROISOPHALATE DERIVATIVE USING ORGANO ALKYL METALLIC COMPOUND TO ALKYLATE AT THE 6 POSITION AND THEN DECARBOXYLATION CLARIANT GMBH (DE) 2002-03-26 US disclosed
EP-1002786-A1 Process for the preparation of trifluorobenzoic acids Clariant GmbH (DE) 2000-05-24 EP disclosed