Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 6/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7098768 | 0.88 | ALDH1A1 (0.46) | F10ALDH1A1F2PRSS1PRSS2 | |
| SCHEMBL7068364 | 0.84 | LTB4R2 (0.43) | F10ALDH1A1TSHRLTB4R2MAPT | |
| SCHEMBL7075244 | 0.84 | F10 (0.39) | F10ALDH1A1F2PRSS1PRSS2 | |
| SCHEMBL7072844 | 0.80 | LTB4R2 (0.40) | ALDH1A1TSHRLTB4R2MAPT | |
| SCHEMBL7089977 | 0.78 | ALDH1A1 (0.38) | F10ALDH1A1TSHR | |
| SCHEMBL7072131 | 0.76 | LTB4R2 (0.43) | ALDH1A1TSHRLTB4R2MAPT | |
| SCHEMBL7094641 | 0.73 | F10 (0.39) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7072311 | 0.73 | L3MBTL1 (0.43) | ALDH1A1TSHRMAPT | |
| SCHEMBL7061973 | 0.72 | F10 (0.39) | F10ALDH1A1F2PRSS1PRSS2 | |
| SCHEMBL7087198 | 0.72 | RAB9A (0.42) | TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030187037-A1 | Acetamide derivatives and the use thereof as inhibitors of coagulation factors xa and viia | MERCK-PATENT GMBH (DE) | 2003-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187037-A1 | Acetamide derivatives and the use thereof as inhibitors of coagulation factors xa and viia | F12, F11, PLAT | F10 17/4885CA12 1051/4885CA1 576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.