Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6311659 | 0.77 | ALDH1A1 (0.38) | ALDH1A1KDM4EGAAMAPTALOX15 | |
| SCHEMBL6311663 | 0.77 | ALDH1A1 (0.38) | ALDH1A1KDM4EGAAMAPTALOX15 | |
| SCHEMBL6311666 | 0.72 | ALDH1A1 (0.35) | ALDH1A1KDM4EGAAMAPTALOX15 | |
| SCHEMBL9622865 | 0.72 | KDM4E (0.57) | ALDH1A1KDM4EGAAMAPTALOX15 | |
| SCHEMBL17774946 | 0.72 | IKBKB (0.49) | ALDH1A1KDM4EGAAMAPTALOX15 | |
| SCHEMBL15200002 | 0.71 | ALDH1A1 (0.47) | ALDH1A1KDM4EGAAMAPTALOX15 | |
| SCHEMBL61025 | 0.70 | ALOX15 (0.50) | ALDH1A1KDM4EGAAMAPTALOX15 | |
| SCHEMBL17774904 | 0.68 | MAP4K1 (0.45) | ALDH1A1KDM4EGAAMAPTALOX15 | |
| SCHEMBL13548437 | 0.67 | TDP1 (0.46) | ALDH1A1ALOX15HPGDTSHRHSD17B10 | |
| SCHEMBL30724396 | 0.67 | TDP1 (0.46) | ALDH1A1ALOX15HPGDTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351921-A1 | NOVEL 1,4-DIAMINO-2-ALKENYL-BENZENE DERIVATIVES AND COLORANTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002057214-A1 | NOVEL 1,4-DIAMINO-2-ALKENYL-BENZENE DERIVATIVES AND COLORANTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-07-25 | — | — | WO | disclosed |