Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | RECQL | P46063 | 4/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2202556 | 0.82 | ALDH1A1 (0.52) | ALOX15HSD17B10CYP3A4GAAMEN1 | |
| SCHEMBL565079 | 0.81 | ALOX15 (0.54) | ALOX15HSD17B10CYP3A4GAAMEN1 | |
| SCHEMBL28728770 | 0.79 | ALOX15 (0.52) | ALOX15HSD17B10CYP3A4GAAMEN1 | |
| SCHEMBL30724396 | 0.78 | TDP1 (0.46) | ALOX15HSD17B10CYP3A4MEN1KMT2A | |
| SCHEMBL84733 | 0.78 | ARG1 (0.48) | ALOX15HSD17B10CYP3A4MEN1MAPT | |
| SCHEMBL13548437 | 0.78 | TDP1 (0.46) | ALOX15HSD17B10CYP3A4MEN1KMT2A | |
| Bromide SCHEMBL28351801 | 0.76 | ARG1 (0.47) | ALOX15HSD17B10CYP3A4MEN1MAPT | |
| Hydrochloric Acid SCHEMBL27786790 | 0.76 | ARG1 (0.47) | ALOX15HSD17B10CYP3A4MEN1MAPT | |
| Hydrochloric Acid SCHEMBL11296739 | 0.76 | TDP1 (0.44) | ALOX15HSD17B10CYP3A4MEN1MAPT | |
| SCHEMBL6571996 | 0.75 | ALDH1A1 (0.44) | ALOX15HSD17B10CYP3A4GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1557157-B1 | Composition for the dyeing of human hair | KPSS KAO GMBH (DE) | 2007-03-07 | — | — | EP | claimed |
| EP-1557157-A1 | Composition for the dyeing of human hair | KPSS-Kao Professional Salon Services GmbH (DE) | 2005-07-27 | — | — | EP | claimed |
| CN-1602836-A | Dye composition comprising at least one oxidation base, 2-chloro-6-methyl-3-aminophenol and 3-methyl-1-phenyl-5-pyrazolone | OREAL (FR) | 2005-04-06 | — | — | CN | claimed |
| WO-2023276668-A1 | COMPOUND, COMPOSITION, FILM, LAMINATE, AND DISPLAY DEVICE | 住友化学株式会社 | 2023-01-05 | — | — | WO | disclosed |
| US-8129525-B2 | Long wavelength thiol-reactive fluorophores | BECTON DICKINSON AND COMPANY (US) | 2012-03-06 | — | — | US | disclosed |
| US-8129525-B2 | Long wavelength thiol-reactive fluorophores | BECTON DICKINSON AND COMPANY (US) | 2012-03-06 | — | — | US | disclosed |
| US-8071794-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON AND COMPANY (US) | 2011-12-06 | — | — | US | disclosed |
| US-8071794-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON AND COMPANY (US) | 2011-12-06 | — | — | US | disclosed |
| US-20110184168-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | BECTON, DICKINSON AND COMPANY (US) | 2011-07-28 | — | — | US | disclosed |
| US-20110184168-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | BECTON, DICKINSON AND COMPANY (US) | 2011-07-28 | — | — | US | disclosed |
| US-7951209-B2 | device comprises at least three compartments, a first compartment that contains the carbonyl compound that is useful for the invention, a second compartment that contains a diaminopyrazole, and a third compartment that contains an oxidizing composition | L'OREAL (FR) | 2011-05-31 | — | — | US | disclosed |
| US-20020046431-A1 | Composition for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one cationic amphiphilic polymer, and dyeing methods | LAURENT FLORENCE (FR) | 2002-04-25 | — | — | US | disclosed |
| US-20020013971-A1 | OXIDATION DYEING COMPOSITION FOR KERATIN FIBRES | MAUBRU MIREILLE (FR) | 2002-02-07 | — | — | US | disclosed |
| US-20020010966-A1 | OXIDATION DYEING COMPOSITION FOR KERATIN FIBRES AND DYEING METHOD USING SAID COMPOSITION | L'OREAL S.A. (FR) | 2002-01-31 | — | — | US | disclosed |
| US-6342078-B1 | OXIDATION COLOR DYES FOR HAIR WITH METAPHENYLENEDIAMINE COUPLERS | L'OREAL, S. A. (FR) | 2002-01-29 | — | — | US | disclosed |
| US-20020004959-A1 | Oxidizing composition and uses for dyeing, for permanently reshaping or for bleaching keratin fibres | L'OREAL S.A. | 2002-01-17 | — | — | US | disclosed |
| US-20010049850-A1 | Mixture containing 2-amino-3-hydroxypyridine coupler and oxidoreductase enzyme | L'OREAL S.A. (FR) | 2001-12-13 | — | — | US | disclosed |
| US-20010044977-A1 | Oxidizing composition and uses for dyeing, for permanently reshaping or for bleaching keratin fibers | L'OREAL S.A. | 2001-11-29 | — | — | US | disclosed |
| US-5989295-A | DYE MIXTURE CONTAINING DYESTUFF AND ACRYLIC CARBOXYLIC ACID-LONG CHAIN ALKYL ACRYLATE COPOLYMER FLOW CONTROL AGENT; HAIR DYES HAVING GREATER LUMINOSITY | L'OREAL (FR) | 1999-11-23 | — | — | US | disclosed |
| US-5578087-A | Dyeing compositions for keratinous fibres based on para-phenylene-diamines, meta-phenylenediamine and benzimidazole derivatives, and dyeing process employing them | L'OREAL (FR) | 1996-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020004959-A1 | Oxidizing composition and uses for dyeing, for permanently reshaping or for bleaching keratin fibres | POLR1C, KRT18, HAGH | ALOX15 3014/4885HSD17B10 483/4885CYP3A4 2120/4885 |
| US-20010049850-A1 | Mixture containing 2-amino-3-hydroxypyridine coupler and oxidoreductase enzyme | POR, QDPR, DPYD | ALOX15 3061/4885HSD17B10 201/4885CYP3A4 339/4885 |
| US-20010044977-A1 | Oxidizing composition and uses for dyeing, for permanently reshaping or for bleaching keratin fibers | KRT18, ALDH1A2, PPOX | ALOX15 2096/4885HSD17B10 268/4885CYP3A4 1570/4885 |
| US-20020013971-A1 | OXIDATION DYEING COMPOSITION FOR KERATIN FIBRES | KRT18, COX6C, MT-CO1 | ALOX15 1551/4885HSD17B10 153/4885CYP3A4 611/4885 |
| US-20020010966-A1 | OXIDATION DYEING COMPOSITION FOR KERATIN FIBRES AND DYEING METHOD USING SAID COMPOSITION | KRT18, QDPR, CYB5R3 | ALOX15 2065/4885HSD17B10 287/4885CYP3A4 313/4885 |
| US-20110184168-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | NUCB2, NDC1, NCBP1 | ALOX15 3704/4885HSD17B10 1607/4885CYP3A4 1548/4885 |
| US-20020046431-A1 | Composition for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one cationic amphiphilic polymer, and dyeing methods | KRT18, ACAD10, OAT | ALOX15 184/4885HSD17B10 11/4885CYP3A4 1288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.