SCHEMBL7073262

SCHEMBL7073262

O=C(OCCCOc1c(Cl)cc(O)cc1Cl)c1ccco1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
LMNA P02545 4/20 0.47
MAPT P10636 4/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
HTT P42858 2/20 0.47
ALOX12 P18054 1/20 0.47
CCR6 P51684 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
KMT2A Q03164 6/20 0.44
TSHR P16473 1/20 0.42
KDM4E B2RXH2 2/20 0.41
MEN1 O00255 1/20 0.41
POLB P06746 1/20 0.41
MAPK10 P53779 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MAPK1 P28482 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7073015 0.82 ALDH1A1 (0.41) ALDH1A1LMNAMAPTSMN1; SMN2HTT
SCHEMBL15256939 0.82 ALDH1A1 (0.59) ALDH1A1LMNAMAPTSMN1; SMN2HTT
SCHEMBL7965659 0.80 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2KMT2ATSHRKDM4E
SCHEMBL8077387 0.79 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2KMT2ATSHRKDM4E
SCHEMBL31337846 0.79 ALDH1A1 (0.59) ALDH1A1LMNAMAPTSMN1; SMN2HTT
SCHEMBL8658023 0.79 TDP1 (0.58) ALDH1A1LMNASMN1; SMN2KMT2ATSHR
SCHEMBL6736151 0.76 ALDH1A1 (0.51) ALDH1A1LMNAMAPTSMN1; SMN2HTT
SCHEMBL8657702 0.76 TDP1 (0.63) ALDH1A1LMNASMN1; SMN2KMT2ATSHR
SCHEMBL11039202 0.75 ALDH1A1 (0.62) ALDH1A1LMNAMAPTSMN1; SMN2HTT
SCHEMBL7071169 0.75 L3MBTL1 (0.59) ALDH1A1LMNAMAPTSMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6589914-B2 The dihalopropene compounds of the general formula (I) have excellent insecticidal/acaricidal activity, so that they are satisfactorily effective for the control of noxious insects, mites and ticks. SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-07-08 US disclosed
US-20030073847-A1 Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2003-04-17 US disclosed
US-6376428-B1 Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-04-23 US disclosed
US-6268313-B1 CONTROLLING INSECTS, MITES, TICKS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-31 US disclosed
US-6071861-A FOR THE CONTROL OF NOXIOUS INSECTS, MITES AND TICKS SUMITOMO CHEMICAL COMPANY, INC. (JP) 2000-06-06 US disclosed
EP-0785923-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2000-04-05 EP disclosed
US-5922880-A CONTROLLING INSECTS, MITES AND TICKS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-07-13 US disclosed
EP-0785923-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1997-07-30 EP disclosed
WO-1996011909-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030073847-A1 Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production DDT, DDC, AADAC ALDH1A1 213/4885LMNA 4375/4885MAPT 3326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.