Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7073997 | 0.89 | F10 (0.61) | F10LMNAMAPTMAPK1L3MBTL1 | |
| Acetic Acid SCHEMBL27552343 | 0.86 | F10 (0.58) | F10LMNAMAPTMAPK1L3MBTL1 | |
| SCHEMBL7074608 | 0.84 | F10 (0.61) | F10LMNAMAPTMAPK1L3MBTL1 | |
| SCHEMBL7071822 | 0.84 | F10 (0.61) | F10LMNAMAPTMAPK1L3MBTL1 | |
| SCHEMBL7076666 | 0.83 | LMNA (0.72) | F10LMNAMAPTMAPK1L3MBTL1 | |
| Acetic Acid SCHEMBL27550450 | 0.83 | F10 (0.57) | F10LMNAMAPTMAPK1L3MBTL1 | |
| SCHEMBL7071611 | 0.82 | F10 (0.59) | F10LMNAMAPTMAPK1L3MBTL1 | |
| Acetic Acid SCHEMBL27574150 | 0.81 | F10 (0.58) | F10LMNAMAPTMAPK1L3MBTL1 | |
| SCHEMBL7074494 | 0.81 | F10 (0.66) | F10LMNAMAPTMAPK1L3MBTL1 | |
| SCHEMBL7074251 | 0.80 | LMNA (0.66) | F10LMNAMAPTMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |