Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27550450 | 0.96 | F10 (0.57) | F10L3MBTL1CNR1MAPTMEN1 | |
| SCHEMBL7073997 | 0.88 | F10 (0.61) | F10L3MBTL1MAPTMEN1KMT2A | |
| Acetic Acid SCHEMBL27552343 | 0.85 | F10 (0.58) | F10L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL7074494 | 0.85 | F10 (0.66) | F10L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL1945511 | 0.85 | L3MBTL1 (0.81) | L3MBTL1CNR1MAPTMEN1KMT2A | |
| SCHEMBL7073647 | 0.84 | F10 (0.57) | F10L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL7077553 | 0.84 | F10 (0.65) | F10L3MBTL1CNR1MAPTMEN1 | |
| SCHEMBL7076666 | 0.84 | LMNA (0.72) | F10L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL7074220 | 0.84 | LMNA (0.71) | F10L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL7071445 | 0.82 | F10 (0.62) | F10L3MBTL1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |