Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.51 |
| ▸ | GPR183 | P32249 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27552343 | 0.97 | F10 (0.58) | F10ALDH1A1MEN1HTTKMT2A | |
| SCHEMBL751828 | 0.91 | ALDH1A1 (0.66) | ALDH1A1MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL7073647 | 0.89 | F10 (0.57) | F10MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL7071822 | 0.88 | F10 (0.61) | F10ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL7076666 | 0.86 | LMNA (0.72) | F10ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL752323 | 0.86 | LMNA (0.72) | ALDH1A1MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL751716 | 0.86 | LMNA (0.72) | ALDH1A1MEN1HTTKMT2ASMN1; SMN2 | |
| Acetic Acid SCHEMBL27550450 | 0.86 | F10 (0.57) | F10ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL735124 | 0.85 | LMNA (0.66) | ALDH1A1MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL7074494 | 0.85 | F10 (0.66) | F10MEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |