Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 11/20 | 0.49 |
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7077837 | 0.90 | ALDH1A1 (0.45) | MMP13MMP2ALDH1A1F2F10 | |
| SCHEMBL7074308 | 0.89 | MMP13 (0.45) | MMP13MMP2MMP1ALDH1A1F2 | |
| SCHEMBL7075400 | 0.88 | F2 (0.45) | MMP13MMP2ALDH1A1F2F10 | |
| SCHEMBL7078814 | 0.88 | MMP13 (0.48) | MMP13MMP2MMP1ALDH1A1F2 | |
| SCHEMBL8359412 | 0.83 | MMP13 (0.42) | MMP13MMP2MMP1ALDH1A1KCNA5 | |
| SCHEMBL7073376 | 0.82 | ALDH1A1 (0.46) | MMP13MMP2MMP1ALDH1A1F2 | |
| SCHEMBL7079059 | 0.81 | ALDH1A1 (0.45) | MMP13MMP2ALDH1A1MEN1KMT2A | |
| SCHEMBL7079124 | 0.81 | ALDH1A1 (0.45) | MMP13MMP2ALDH1A1MEN1KMT2A | |
| SCHEMBL7077874 | 0.79 | F2 (0.46) | MMP2MMP1ALDH1A1F2F10 | |
| SCHEMBL7078927 | 0.77 | CA12 (0.44) | MMP13MMP2MMP1ALDH1A1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059872-A1 | AVB3 AND AVB5 INTEGRIN ANTAGONISTS AND METHODS OF TREATING DISEASES OR CONDITIONS ASSOCIATED WITH AVB3 AND AVB5 INTEGRINS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |